Medical Abnormalities

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A study by Stanford University researchers demonstrated abnormalities in the brains of illness sufferers compared to those of healthy controls.

 

More than 500 peer-reviewed articles have been published demonstrating a wide variety of physiological abnormalities in patients with “chronic fatigue syndrome” (a broader condition that currently encompasses patients with the more specifically defined condition of myalgic encephalomyelitis).

To read the citations and a brief description of each article, please click on the topic links below.

The full abstract for each article can be easily found by typing the PMID number into the PubMed search engine.

A PDF summary (238 pages) provides the same information presented at the links but in an easily printable format.

Please note that most of the studies presented here focus on “CFS” or “ME/CFS” patients rather than M.E. patients, and therefore that the samples tend to be diluted with individuals who are only mildly ill or who may have totally different conditions.

While many abnormalities obviously have been found even in these broad groups of patients, the few studies that have focused on M.E. patients have almost always demonstrated much more alarming abnormalities with much stronger effect sizes.

A priority for those concerned about this disease thus may be to make certain that more research looking specifically at M.E. patients (especially severely ill M.E. patients) takes place.

References presented in this section were last updated on April 4, 2016. Newer articles will be added soon – please sign up for email updates from this website to be informed when that occurs.

 

General Issues

Overview

Comparison with Other Conditions

 

Neurological Issues

Brain Abnormalities

Cognitive Impairment

 

Cardiovascular Issues

Cardiac Issues

Orthostatic Intolerance

Tilt Table Test

Other Cardiovascular Issues

 

Exercise Issues

Exercise & Activity Intolerance

 

Mitochondrial Issues

Mitochondrial Issues

 

Immune Issues

Cytokines & Complement

Natural Killer Cells

Oxidative Stress & Inflammation

Rnase L

Additional Immune Abnormalities

 

Infections

Borna Disease

Coxiella Burnetii

Enteroviruses

Herpesviruses

Mycoplasma

Parvovirus B19

Stealth Virus

Other Infections

 

Gastrointestinal Issues

Candida

Gut Issues

 

Additional Issues

Cancer Risk

Channelopathies

Endocrine System

Gait Issues

Muscle Issues

Pain Issues

Sleep Issues

 

Symptoms & Labs

Laboratory Abnormalities

Physical Abnormalities

Physical Symptoms

 

Nutritional Issues

Carnitine

Lipids

Other Nutrients

 

Genetics

HLA

Other Genetics

 

Updated April 4, 2016

 

Information on this website is presented by Paradigm Change. Links on this page are in orange (no underlining).