Following is a list of articles about abnormalities with Q fever (coxiella burnetii) in ME and CFS.
Links to the more than 1,000 peer-reviewed journal articles are listed on the ME and CFS Medical Abnormalities page of this website.
Strauss B, Löschau M, Seidel T, Stallmach A, Thomas A. Are fatigue symptoms and chronic fatigue syndrome following Q fever infection related to psychosocial variables? J Psychosom Res. 2012 Apr;72(4):300-4. PMID: 22405225
Although in the researchers’ sample fatigue symptoms were common among Q fever patients, they found no increased prevalence of CFS in contrast to several other studies.
Ledina D, Bradarić N, Milas I, Ivić I, Brncić N, Kuzmicić N. Chronic fatigue syndrome after Q fever. Med Sci Monit. 2007 Jul;13(7):CS88-92. PMID: 17599032
Coxiella burnetii infection may be involved in the evolution of CFS.
Iwakami E, Arashima Y, Kato K, Komiya T, Matsukawa Y, Ikeda T, Arakawa Y, Oshida S. Treatment of chronic fatigue syndrome with antibiotics: pilot study assessing the involvement of Coxiella burnetii infection. Intern Med. 2005 Dec;44(12):1258-63. PMID: 16415546
Four CFS patients (the CFS group) and 54 controls [the post-Q fever fatigue syndrome (QFS) group] positive for C. burnetii were treated mainly with minocycline or doxycycline (100 mg/day) for 3 months. After treatment, all 58 patients tested negative for C. burnetii infection. In the CFS group, health did not improve.
Ayres JG, Flint N, Smith EG, Tunnicliffe WS, Fletcher TJ, Hammond K, Ward D, Marmion BP. Post-infection fatigue syndrome following Q fever. QJM. 1998 Feb;91(2):105-23. PMID: 9578893
The authors looked at a group of people who were infected with Q fever in 1989, finding CFS in 42.3% of cases and 26% of controls.
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