Fusarium Literature – Anorexia & Weight Loss



Zhang J, Jia H, Wang Q, Zhang Y, Wu W, Zhang H. Role of Peptide YY3-36 and Glucose-dependent Insulinotropic Polypeptide in Anorexia Induction by Trichothecences T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol and Neosolaniol. Toxicol Sci. 2017 Jun 28. PMID: 28666375

Jia H, Wu WD, Lu X, Zhang J, He CH, Zhang HB. Role of Glucagon-Like Peptide-1and Gastric Inhibitory Peptide in Anorexia Induction Following Oral Exposure to the Trichothecene Mycotoxin Deoxynivalenol (Vomitoxin). Toxicol Sci. 2017 Jun 19. PMID: 28633506

Peng Z, Chen L, Xiao J, Zhou X, Nüssler AK, Liu L, Liu J, Yang W. Review of mechanisms of deoxynivalenol-induced anorexia: The role of gut microbiota. J Appl Toxicol. 2017 Sep;37(9):1021-1029. PMID: 28466983

Gajęcka M, Tarasiuk M, Zielonka Ł, Dąbrowski M, Gajęcki M. Risk assessment for changes in the metabolic profile and body weights of pre-pubertal gilts during long-term monotonic exposure to low doses of zearalenone (ZEN). Res Vet Sci. 2016 Dec;109:169-180. PMID: 27892868

Male D, Wu W, Mitchell NJ, Bursian S, Pestka JJ, Wu F. Modeling the emetic potencies of food-borne trichothecenes by benchmark dose methodology. Food Chem Toxicol. 2016 Aug;94:178-85. PMID: 27292944

Tominaga M, Momonaka Y, Yokose C, Tadaishi M, Shimizu M, Yamane T, Oishi Y, Kobayashi-Hattori K. Anorexic action of deoxynivalenol in hypothalamus and intestine. Toxicon. 2016 Aug;118:54-60. PMID: 27090011

Clark ES, Flannery BM, Pestka JJ. Murine Anorectic Response to Deoxynivalenol (Vomitoxin) Is Sex-Dependent. Toxins (Basel). 2015 Jul 29;7(8):2845-59. PMID: 26230710

Alizadeh A, Braber S, Akbari P, Garssen J, Fink-Gremmels J. Deoxynivalenol Impairs Weight Gain and Affects Markers of Gut Health after Low-Dose, Short-Term Exposure of Growing Pigs. Toxins (Basel). 2015 Jun 9;7(6):2071-95. PMID: 26067367

Wu W, Zhou HR, Pan X, Pestka JJ. Comparison of Anorectic Potencies of the Trichothecenes T-2 Toxin, HT-2 Toxin and Satratoxin G to the Ipecac Alkaloid Emetine. Toxicol Rep. 2015;2:238-251. PMID: 25932382

Wu W, Zhang H. Role of tumor necrosis factor-α and interleukin-1β in anorexia induction following oral exposure to the trichothecene deoxynivalenol (vomitoxin) in the mouse. J Toxicol Sci. 2014;39(6):875-86. PMID: 25392278

Wu W, Zhou HR, He K, Pan X, Sugita-Konishi Y, Watanabe M, Zhang H, Pestka JJ. Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicol Sci. 2014 Apr;138(2):278-89. PMID: 24385417

Flannery Brenna M., He Kaiyu, Pestka James J.. Deoxynivalenol-induced weight loss in the diet-induced obese mouse is reversible and PKR-independent. Toxicology letters.  2013;221:9–14.

Wu Wenda, Flannery Brenna M., Sugita-Konishi Yoshiko, Watanabe Maiko, Zhang Haibin, Pestka James J.. Comparison of murine anorectic responses to the 8-ketotrichothecenes 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, fusarenon X and nivalenol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2012;50:2056–2061.

Tan Diana C., Flematti Gavin R., Ghisalberti Emilio L., et al. Mycotoxins produced by Fusarium species associated with annual legume pastures and ’sheep feed refusal disorders’ in Western Australia. Mycotoxin research. 2011;27:123–135.

Amuzie C. J., Flannery B. M., Ulrich A. M., Pestka J. J.. Effects of deoxynivalenol consumption on body weight and adiposity in the diet-induced obese mouse. Journal of toxicology and environmental health. Part A.  2011;74:658–667.

Flannery Brenna M., Wu Wenda, Pestka James J.. Characterization of deoxynivalenol-induced anorexia using mouse bioassay. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2011;49:1863–1869.

Seeling K., Dänicke S., Ueberschär K. H., Lebzien P., Flachowsky G.. On the effects of Fusarium toxin-contaminated wheat and the feed intake level on the metabolism and carry over of zearalenone in dairy cows. Food additives and contaminants. 2005;22:847–855.

Pestka J. J., Zhou H-R R.. Effects of tumor necrosis factor type 1 and 2 receptor deficiencies on anorexia, growth and IgA dysregulation in mice exposed to the trichothecene vomitoxin. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2002;40:1623–1631.

Szkudelska Katarzyna, Szkudelski Tomasz, Nogowski Leszek. Short-time deoxynivalenol treatment induces metabolic disturbances in the rat. Toxicology letters. 2002;136:25–31.

Brake J., Hamilton P. B., Kittrell R. S.. Effects of the trichothecene mycotoxin diacetoxyscirpenol on feed consumption, body weight, and oral lesions of broiler breeders. Poultry science. 2000;79:856–863.

Prelusky D. B.. Effect of intraperitoneal infusion of deoxynivalenol on feed consumption and weight gain in the pig. Natural toxins. 1997;5:121–125.

Rotter B. A., Prelusky D. B., Thompson B. K.. The role of tryptophan in DON-induced feed rejection. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1996;31:1279–1288.

Ossenkopp K. P., Hirst M., Rapley W. A.. Deoxynivalenol (vomitoxin)-induced conditioned taste aversions in rats are mediated by the chemosensitive area postrema. Pharmacology, biochemistry, and behavior. 1994;47:363–367.

Fioramonti J., Dupuy C., Dupuy J., Bueno L.. The mycotoxin, deoxynivalenol, delays gastric emptying through serotonin-3 receptors in rodents. The Journal of pharmacology and experimental therapeutics. 1993;266:1255–1260.

Ademoyero A. A., Hamilton P. B.. Mouth lesions in broiler chickens caused by scirpenol mycotoxins. Poultry science. 1991;70:2082–2089.

Moré J., Galtier P., Eeckhoutte C.. Effect of low doses of a trichothecene mycotoxin (diacetoxyscirpenol) on rat gastric glycoproteins: a histochemical study. Toxicology letters. 1990;50:173–178.

Ademoyero A. A., Hamilton P. B.. Influence of degree of acetylation of scirpenol mycotoxins on feed refusal by chickens. Poultry science. 1989;68:854–856.

Fekete S., Tamas J., Vanyi A., Glavits R., Bata A.. Effect of T-2 toxin on feed intake, digestion and pathology of rabbits. Laboratory animal science. 1989;39:603–606.

Marpegan M. R., Perfumo C. J., Godoy H. M., Miguel M., Diaz E., Risso M. A.. Feed refusal of pigs caused by Fusarium mycotoxins in Argentina. Zentralblatt für Veterinärmedizin. Reihe A. 1988;35:610–616.

Clark D. E., Wellman P. J., Harvey R. B., Lerma M. S.. Effects of vomitoxin (deoxynivalenol) on conditioned saccharin aversion and food consumption in adult rats. Pharmacology, biochemistry, and behavior. 1987;27:247–252.

Matsuoka Y., Kubota K.. Studies on mechanisms of diarrhea induced by fusarenon-X, a trichothecene mycotoxin from Fusarium species: fusarenon-X-induced diarrhea is not mediated by cyclic nucleotides. Toxicology and applied pharmacology. 1987;91:326–332.

Pestka J. J., Lin W. S., Miller E. R.. Emetic activity of the trichothecene 15-acetyldeoxynivalenol in swine. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1987;25:855–858.

Pestka J. J., Lin W. S., Forsell J. H.. Decreased feed consumption and body-weight gain in the B6C3F1 mouse after dietary exposure to 15-acetyldeoxynivalenol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1986;24:1309–1313.

Burditt S. J., Hagler W. M., Hamilton P. B.. Survey of molds and mycotoxins for their ability to cause feed refusal in chickens. Poultry science. 1983;62:2187–2191.

Burditt S. J., Hagler W. M., Hutchins J. E., Hamilton P. B.. Models of feed refusal syndrome in poultry. Poultry science. 1983;62:2158–2163.

Osborne D. J., Huff W. E., Hamilton P. B., Burmeister H. R.. Comparison of ochratoxin, aflatoxin, and T-2 toxin for their effects on selected parameters related to digestion and evidence for specific metabolism of carotenoids in chickens. Poultry science. 1982;61:1646–1652.

Vesonder R. F., Ellis J. J., Rohwedder W. K.. Swine refusal factors elaborated by Fusarium strains and identified as trichothecenes. Applied and environmental microbiology. 1981;41:323–324.

Matsuoka Y., Kubota K.. Studies on mechanisms of diarrhea induced by fusarenon-X a trichothecene mycotoxin from Fusarium species. Toxicology and applied pharmacology. 1981;57:293–301.

Burmeister H. R., Vesonder R. F., Kwolek W. F.. Mouse bioassay for Fusarium metabolites: rejection or acceptance when dissolved in drinking water. Applied and environmental microbiology. 1980;39:957–961.

Vesonder R. F., Ciegler A., Burmeister H. R., Jensen A. H.. Acceptance by swine and rats of corn amended with trichothecenes. Applied and environmental microbiology. 1979;38:344–346.

Chi M. S., Mirocha C. J.. Necrotic oral lesions in chickens fed diacetoxyscirpenol, T-2 toxin, and crotocin. Poultry science. 1978;57:807–808.

Forsyth D. M., Yoshizawa T., Morooka N., Tuite J.. Emetic and refusal activity of deoxynivalenol to swine. Applied and environmental microbiology. 1977;34:547–552.

Kotsonis F. N., Smalley E. B., Ellison R. A., Gale C. M.. Feed refusal factors in pure cultures of Fusarium roseum ’graminearum’. Applied microbiology. 1975;30:362–368.