Fusarium Literature – Thymus



Li D, Ma H, Ye Y, Ji C, Tang X, Ouyang D, Chen J, Li Y, Ma Y. Deoxynivalenol induces apoptosis in mouse thymic epithelial cells through mitochondria-mediated pathway. Environ Toxicol Pharmacol. 2014 Jul;38(1):163-71. PMID: 24952344

Li Daotong, Ye Yaqiong, Deng Li, et al. Gene expression profiling analysis of deoxynivalenol-induced inhibition of mouse thymic epithelial cell proliferation. Environmental toxicology and pharmacology. 2013;36:557–566.

Kol Sandra W., Hendriksen Peter J., Loveren Henk, Peijnenburg Ad. The effects of deoxynivalenol on gene expression in the murine thymus. Toxicology and applied pharmacology. 2011;250:299–311.

Osman Ahmed M., Pennings Jeroen L., Blokland Marco, Peijnenburg Ad, Loveren Henk. Protein expression profiling of mouse thymoma cells upon exposure to the trichothecene deoxynivalenol (DON): implications for its mechanism of action. Journal of immunotoxicology. 2010;7:147–156.

Poapolathep Amnart, Kumagai Susumu, Suzuki Hodaka, Doi Kunio. Development of early apoptosis and changes in T-cell subsets in mouse thymocyte primary cultures treated with nivalenol. Experimental and molecular pathology. 2004;77:149–152.

Li S., Ouyang Y., Yang G. H., Pestka J. J.. Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol). Toxicology and applied pharmacology. 2000;163:17–25.

Murshedul A. M., Nagase M., Yoshizawa T., Sakato N.. Thymocyte apoptosis by T-2 toxin in vivo in mice is independent of Fas/Fas ligand system. Bioscience, biotechnology, and biochemistry. 2000;64:210–213.

Lee M. G., Li S., Jarvis B. B., Pestka J. J.. Effects of satratoxins and other macrocyclic trichothecenes on IL-2 production and viability of EL-4 thymoma cells. Journal of toxicology and environmental health. Part A. 1999;57:459–474.

Islam Z., Nagase M., Yoshizawa T., Yamauchi K., Sakato N.. T-2 toxin induces thymic apoptosis in vivo in mice. Toxicology and applied pharmacology. 1998;148:205–214.

Miura K., Nakajima Y., Yamanaka N., Terao K., Shibato T., Ishino S.. Induction of apoptosis with fusarenon-X in mouse thymocytes. Toxicology. 1998;127:195–206.

Islam Z., Nagase M., Ota A., Ueda S., Yoshizawa T., Sakato N.. Structure-function relationship of T-2 toxin and its metabolites in inducing thymic apoptosis in vivo in mice. Bioscience, biotechnology, and biochemistry. 1998;62:1492–1497.

Dong W., Azcona-Olivera J. I., Brooks K. H., Linz J. E., Pestka J. J.. Elevated gene expression and production of interleukins 2, 4, 5, and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma. Toxicology and applied pharmacology. 1994;127:282–290.

Ohtani K., Murakami H., Shibuya O., et al. Antitumor activity of T-2 toxin-conjugated monoclonal antibody to murine thymoma. The Japanese journal of experimental medicine. 1990;60:57–65.

Lafarge-Frayssinet C., Lespinats G., Lafont P., et al. Immunosuppressive effects of Fusarium extracts and trichothecenes: blastogenic response of murine splenic and thymic cells to mitogens. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1979;160:302–311.