Fusarium Literature – Protein Synthesis



Agrawal M, Bhaskar AS, Lakshmana Rao PV. Involvement of mitogen-activated protein kinase pathway in T-2 toxin-induced cell cycle alteration and apoptosis in human neuroblastoma cells. Mol Neurobiol. 2015;51(3):1379-94. PMID: 25084755

Pan X, Whitten DA, Wilkerson CG, Pestka JJ. Deoxynivalenol-induced translation inhibition and ribotoxic stress. Toxicol Sci. 2014 Mar;138(1):217-33. PMID: 24284785

Goyarts Tanja, Grove Nicola, Dänicke Sven. Effects of the Fusarium toxin deoxynivalenol from naturally contaminated wheat given subchronically or as one single dose on the in vivo protein synthesis of peripheral blood lymphocytes and plasma proteins in the pig. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2006;44:1953–1965.

Dänicke S., Goyarts T., Döll S., Grove N., Spolders M., Flachowsky G.. Effects of the Fusarium toxin deoxynivalenol on tissue protein synthesis in pigs. Toxicology letters. 2006;165:297–311.

Zhou Hui-Ren R., Lau Allan S., Pestka James J.. Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response. Toxicological sciences : an official journal of the Society of Toxicology. 2003;74:335–344.

Meloche J. L., Smith T. K.. Altered tissue amino acid metabolism in acute T-2 toxicosis. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1995;210:260–265.

Iwata M., Herrington J., Zager R. A.. Protein synthesis inhibition induces cytoresistance in cultured human proximal tubular (HK-2) cells. The American journal of physiology. 1995;268.

Leatherman D. L., Middlebrook J. L.. Effect of emetine on T-2 toxin-induced inhibition of protein synthesis in mammalian cells. The Journal of pharmacology and experimental therapeutics. 1993;266:741–748.

Raju R., Kolakofsky D.. Inhibitors of protein synthesis inhibit both La Crosse virus S-mRNA and S genome syntheses in vivo. Virus research. 1986;5:1–9.

Ehrlich K. C., Daigle K. W.. Protein synthesis by mammalian cells treated with C-3-modified analogs of the 12,13-epoxytrichothecenes T-2 and T-2 tetraol. Applied and environmental microbiology. 1985;50:914–918.

Rosenstein Y., Lafarge-Frayssinet C.. Inhibitory effect of Fusarium T2-toxin on lymphoid DNA and protein synthesis. Toxicology and applied pharmacology.  1983;70:283–288.

Smith T. K.. Influence of mycotoxins on protein and amino acid utilization. Federation proceedings. 1982;41:2828–2832.

Cundliffe E., Davies J. E.. Inhibition of initiation, elongation, and termination of eukaryotic protein synthesis by trichothecene fungal toxins. Antimicrobial agents and chemotherapy. 1977;11:491–499.

Liao L. L., Grollman A. P., Horwitz S. B.. Mechanism of action of the 12,13-epoxytrichothecene, anguidine, an inhibitor of protein synthesis. Biochimica et biophysica acta. 1976;454:273–284.

Cundliffe E., Cannon M., Davies J.. Mechanism of inhibition of eukaryotic protein synthesis by trichothecene fungal toxins. Proceedings of the National Academy of Sciences of the United States of America. 1974;71:30–34.