Fusarium Literature – Cytotoxicity



Yang D, Jiang T, Lin P, Chen H, Wang L, Wang N, Zhao F, Tang K, Zhou D, Wang A, Jin Y. Apoptosis inducing factor gene depletion inhibits zearalenone-induced cell death in a goat Leydig cell line. Reprod Toxicol. 2017 Jan;67:129-139. PMID: 28011299

Wentzel JF, Lombard MJ, Du Plessis LH, Zandberg L. Evaluation of the cytotoxic properties, gene expression profiles and secondary signalling responses of cultured cells exposed to fumonisin B1, deoxynivalenol and zearalenone mycotoxins. Arch Toxicol. 2017 May;91(5):2265-2282. PMID: 27757495

Springler A, Hessenberger S, Reisinger N, Kern C, Nagl V, Schatzmayr G, Mayer E. Deoxynivalenol and its metabolite deepoxy-deoxynivalenol: multi-parameter analysis for the evaluation of cytotoxicity and cellular effects. Mycotoxin Res. 2017 Feb;33(1):25-37. PMID: 27817099

Sutjarit S, Poapolathep A. Fusarenon-X-induced apoptosis in the liver, kidney, and spleen of mice. J Toxicol Pathol. 2016 Jul;29(3):207-11. PMID: 27559248

Shen L, Zhu L, Tan Q, Wan D, Xie J, Peng J. New cytotoxic trichothecene macrolide epimers from endophytic Myrothecium roridum IFB-E012. J Antibiot (Tokyo). 2016 Aug;69(8):652-5. PMID: 27406908

Stopa E, Babińska I, Zielonka Ł, Gajęcki M, Gajęcka M. Immunohistochemical evaluation of apoptosis and proliferation in the mucous membrane of selected uterine regions in pre-pubertal bitches exposed to low doses of zearalenone. Pol J Vet Sci. 2016;19(1):175-86. PMID: 27096802

Fernández-Blanco C, Frizzell C, Shannon M, Ruiz MJ, Connolly L. An in vitro investigation on the cytotoxic and nuclear receptor transcriptional activity of the mycotoxins fumonisin B1 and beauvericin. Toxicol Lett. 2016 Aug 22;257:1-10. PMID: 27234500

Deng C, Ji C, Qin W, Cao X, Zhong J, Li Y, Srinivas S, Feng Y, Deng X. Deoxynivalenol inhibits proliferation and induces apoptosis in human umbilical vein endothelial cells. Environ Toxicol Pharmacol. 2016 Apr;43:232-41. PMID: 27037652

Riedel S, Abel S, Burger HM, van der Westhuizen L, Swanevelder S, Gelderblom WC. Differential modulation of the lipid metabolism as a model for cellular resistance to fumonisin B1-induced cytotoxic effects in vitro. Prostaglandins Leukot Essent Fatty Acids. 2016 Jun;109:39-51. PMID: 27269712

Xu ML, Hu J, Guo BP, Niu YR, Xiao C, Xu YX. Exploration of intrinsic and extrinsic apoptotic pathways in zearalenone-treated rat sertoli cells. Environ Toxicol. 2016 Dec;31(12):1731-1739. PMID: 26460601

Guerrero-Netro HM, Chorfi Y, Price CA. Effects of the mycotoxin deoxynivalenol on steroidogenesis and apoptosis in granulosa cells. Reproduction. 2015 Jun;149(6):555-61. PMID: 25731188

Singh S, Banerjee S, Chattopadhyay P, Borthakur SK, Veer V. Deoxynivalenol induces cytotoxicity and genotoxicity in animal primary cell culture. Toxicol Mech Methods. 2015 Mar;25(3):184-91. PMID: 25578892

Lin P, Chen F, Sun J, Zhou J, Wang X, Wang N, Li X, Zhang Z, Wang A, Jin Y. Mycotoxin zearalenone induces apoptosis in mouse Leydig cells via an endoplasmic reticulum stress-dependent signalling pathway. Reprod Toxicol. 2015 Apr;52:71-7. PMID: 25720297

Gu Y, Chen X, Shang C, Singh K, Barzegar M, Mahdavian E, Salvatore BA, Jiang S, Huang S. Fusarochromanone induces G1 cell cycle arrest and apoptosis in COS7 and HEK293 cells. PLoS One. 2014 Nov 10;9(11):e112641. PMID: 25384025

Wang HW, Wang JQ, Zheng BQ, Li SL, Zhang YD, Li FD, Zheng N. Cytotoxicity induced by ochratoxin A, zearalenone, and α-zearalenol: effects of individual and combined treatment. Food Chem Toxicol. 2014 Sep;71:217-24. PMID: 24952310

Wang Y, Zheng W, Bian X, Yuan Y, Gu J, Liu X, Liu Z, Bian J. Zearalenone induces apoptosis and cytoprotective autophagy in primary Leydig cells. Toxicol Lett. 2014 Apr 21;226(2):182-91. PMID: 24530352

Zhuang Z, Yang D, Huang Y, Wang S. Study on the apoptosis mechanism induced by T-2 toxin. PLoS One. 2013 Dec 26;8(12):e83105. PMID: 24386148

Nielsen Carina, Casteel Maximilian, Didier Andrea, Dietrich Richard, Märtlbauer Erwin. Trichothecene-induced cytotoxicity on human cell lines. Mycotoxin research.  2009;25:77–84.

Ge Hui Ming M., Jiao Rui Hua H., Zhang Yu Fei F., Zhang Jie, Wang Yu Rong R., Tan Ren Xiang X.. Cytotoxicity and phytotoxicity of trichothecene macrolides from Myrothecium gramminum. Planta medica.  2009;75:227–229.

Chen Jing-hong H., Cao Jun-ling L., Chu Yong-lie L., Wang Zhi-lun L., Yang Zhan-tian T., Wang Hong-lin L.. T-2 toxin-induced apoptosis involving Fas, p53, Bcl-xL, Bcl-2, Bax and caspase-3 signaling pathways in human chondrocytes. Journal of Zhejiang University. Science. B.  2008;9:455–463.

Huang Peixin, Akagawa Keisuke, Yokoyama Yoshiko, Nohara Kazunari, Kano Kazutaka, Morimoto Kanehisa. T-2 toxin initially activates caspase-2 and induces apoptosis in U937 cells. Toxicology letters.  2007;170:1–10.

Chen Jing-hong H., Chu Yong-lie L., Cao Jun-ling L., et al. [Effect of NO and Fas pathway on T-2 induced apoptosis in chondrocytes]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.  2006;37:583–586.

Ivanova Lada, Skjerve Eystein, Eriksen Gunnar S., Uhlig Silvio. Cytotoxicity of enniatins A, A1, B, B1, B2 and B3 from Fusarium avenaceum. Toxicon.  2006;47:868–876.

Albarenque Stella Maris M., Doi Kunio. T-2 toxin-induced apoptosis in rat keratinocyte primary cultures. Experimental and molecular pathology.  2005;78:144–149.

Calvert T. W., Aidoo K. E., Candlish A. G., Fuat Mohd R.. Comparison of in vitro cytotoxicity of Fusarium mycotoxins,deoxynivalenol, T-2 toxin and zearalenone on selected human epithelial cell lines. Mycopathologia.  2005;159:413–419.

Venkatesh P. Kamala, Vairamuthu S., Balachandran C., Manohar B. Murali, Raj G. Dhinakar. Induction of apoptosis by fungal culture materials containing cyclopiazonic acid and T-2 toxin in primary lymphoid organs of broiler chickens. Mycopathologia.  2005;159:393–400.

Heidari Mahnaz, Ghazi-Khansari Mahmmoud, Khoshnoodi Jalal, Shokri Fazel. Comparative Measurement of In Vitro T-2 Toxin Cytotoxicity using Three Different Cytotoxicity Assays. Toxicology mechanisms and methods.  2003;13:153–157.

Miura Katsuhiro, Aminova Leila, Murayama Yuichi. Fusarenon-X induced apoptosis in HL-60 cells depends on caspase activation and cytochrome c release. Toxicology.  2002;172:103–112.

Yang G. H., Jarvis B. B., Chung Y. J., Pestka J. J.. Apoptosis induction by the satratoxins and other trichothecene mycotoxins: relationship to ERK, p38 MAPK, and SAPK/JNK activation. Toxicology and applied pharmacology.  2000;164:149–160.

Wang H., Zhang X.. Recent progress in the study of common fusarium mycotoxins on apoptosis of cells. Wei sheng yan jiu = Journal of hygiene research.  2000;29:181–183.

Widestrand J., Lundh T., Pettersson H., Lindberg J. E.. Cytotoxicity of four trichothecenes evaluated by three colorimetric bioassays.  Mycopathologia.  1999;147:149–155.

Sugamata M., Hattori T., Ihara T., Okumura H., Yoshino N., Ueno Y.. Fine structural changes and apoptotic cell death by T-2 mycotoxin. The Journal of toxicological sciences.  1998;23 Suppl 2:148–154.

Ihara T., Sugamata M., Sekijima M., Okumura H., Yoshino N., Ueno Y.. Apoptotic cellular damage in mice after T-2 toxin-induced acute toxicosis.  Natural toxins.  1997;5:141–145.

Yoshino N., Takizawa M., Akiba H., et al. Transient elevation of intracellular calcium ion levels as an early event in T-2 toxin-induced apoptosis in human promyelotic cell line HL-60. Natural toxins.  1996;4:234–241.

Babich H., Borenfreund E.. Cytotoxicity of T-2 toxin and its metabolites determined with the neutral red cell viability assay. Applied and environmental microbiology.  1991;57:2101–2103.