Aflatoxin Literature: Neurological System



Souto NS, Claudia Monteiro Braga A, Lutchemeyer de Freitas M, Rechia Fighera M, Royes LFF, Schneider Oliveira M, Furian AF. Aflatoxin B1 reduces non-enzymatic antioxidant defenses and increases protein kinase C activation in the cerebral cortex of young rats. Nutr Neurosci. 2017 Jan 24:1-8. PMID: 28116978

Bahey NG, Abd Elaziz HO, Gadalla KK. Toxic effect of aflatoxin B1 and the role of recovery on the rat cerebral cortex and hippocampus. Tissue Cell. 2015 Dec;47(6):559-66. PMID: 26380901

Qureshi H, Hamid SS, Ali SS, Anwar J, Siddiqui AA, Khan NA. Cytotoxic effects of aflatoxin B1 on human brain microvascular endothelial cells of the blood-brain barrier. Med Mycol. 2015 May;53(4):409-16. PMID: 25851265

Tanaka T, Mizukami S, Hasegawa-Baba Y, Onda N, Sugita-Konishi Y, Yoshida T, Shibutani M. Developmental exposure of aflatoxin B1 reversibly affects hippocampal neurogenesis targeting late-stage neural progenitor cells through suppression of cholinergic signaling in rats. Toxicology. 2015 Oct 2;336:59-69. PMID: 26260870

Trebak F, Alaoui A, Alexandre D, El Ouezzani S, Anouar Y, Chartrel N, Magoul R. Impact of aflatoxin B1 on hypothalamic neuropeptides regulating feeding behavior. Neurotoxicology. 2015 Jul;49:165-73. doi: 10.1016/j.neuro.2015.06.008. Epub 2015 Jun 30. PMID: 26141519

D’Angelo A., Bellino C., Alborali G. L., et al. Neurological signs associated with aflatoxicosis in Piedmontese calves. The Veterinary record. 2007;160:698–700.

Cometa Maria Francesca F., Lorenzini Paola, Fortuna Stefano, Volpe Maria Teresa T., Meneguz Annarita, Palmery Maura. In vitro inhibitory effect of aflatoxin B1 on acetylcholinesterase activity in mouse brain. Toxicology. 2005;206:125–135.

Stĕtinová V., Grossmann V., Kvĕtina J., Srámek B.. Effects of aflatoxin B1 on the sensitivity of the rat central nervous system to pentobarbital-Na racemate. Polish journal of pharmacology. 1995;47:393–399.

Kimbrough T. D., Llewellyn G. C., Weekley L. B.. The effect of aflatoxin B1 exposure on serotonin metabolism: response to a tryptophan load. Metabolic brain disease. 1992;7:175–182.

Weekley L. B., O’Rear C. E., Kimbrough T. D., Llewellyn G. C.. Differential changes in rat brain tryptophan, serotonin and tyrosine levels following acute aflatoxin B1 treatment. Toxicology letters. 1989;47:173–177.

Weekley L. B., Kimbrough T. D., Llewellyn G. C.. Disturbances in tryptophan metabolism in rats following chronic dietary aflatoxin treatment. Drug and chemical toxicology. 1985;8:145–154.

Coulombe R. A., Sharma R. P.. Effect of repeated dietary exposure of aflatoxin B1 on brain biogenic amines and metabolites in the rat. Toxicology and applied pharmacology. 1985;80:496–501.

Ahmed N., Singh U. S.. Effect of aflatoxin B1 on brain serotonin and catecholamines in chickens. Toxicology letters. 1984;21:365–367.

Weekley L. B., Llewellyn G. C.. Activities of tryptophan-metabolizing enzymes in liver and brain of rats treated with aflatoxins. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1984;22:65–68.

Egbunike G. N., Ikegwuonu F. I.. Effect of aflatoxicosis on acetylcholinesterase activity in the brain and adenohypophysis of the male rat. Neuroscience letters. 1984;52:171–174.

Ikegwuonu F. I.. The neurotoxicity of aflatoxin B1 in the rat. Toxicology. 1983;28:247–259.

Weekley L. B., Morgan J. D., Rea F. W., Kimbrough T. D., Llewellyn G. C.. Alterations of brain and intestine serotonin levels in hamsters pretreated with dietary aflatoxin. Cancer letters. 1978;5:75–80.

Shankarmurti A., Sreenivasamurthy V., Parpia H. A.. Cannibalistic behaviour of mother albino rats fed aflatoxin. Indian journal of experimental biology. 1972;10:307–308.

Dickerson L. A.. The effects of aflatoxin B1 on the nervous system of young rabbits. The West Virginia medical journal. 1970;66.

Kato R., Takanaka A., Onoda K., Omori Y.. Different effect of aflatoxin on the induction of tryptophan oxygenase and of microsomal drug-hydroxylase system. Journal of biochemistry. 1970;68:589–592.