Dr. Jill Carnahan on “Low Dose Naltrexone”
Jill Carnahan, M.D., wrote an article on “Low Dose Naltrexone: The New Treatment You’ve Never Heard of.”
From the article:
The use of LDN for chronic disorders is still experimental and considered off-label. This doesn’t stop progressive doctors from prescribing it due to it’s safety profile. The typical dose of LDN is a compounded immediate release tablet from 1.5 to 4.5mg taken at bedtime. The few reported side effects may be related to opioid blockade at night. Occasionally patients report anxiety, insomnia, vivid dreaming or nightmares. There are a portion of patients who already have elevated opioids that may not tolerate the drug. To avoid side effects, I generally start patients on half of intended dose and increase after 7-10 days. If they still report symptoms, we move the dosing earlier in the day and may still get a beneficial effect.
Low Dose Naltrexone is an oral medication, generic, inexpensive, and non-toxic, and has been documented to alter the course of both neoplasias and autoimmune diseases such as Crohn’s and multiple sclerosis, making it an attractive and effective therapeutic agent.
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