Glyphosate Research Literature

 

Overview Articles

 McHenry LB. The Monsanto Papers: Poisoning the scientific well. Int J Risk Saf Med. 2018;29(3-4):193-205. PMID: 29843257

Krimsky S, Gillam C. Roundup litigation discovery documents: implications for public health and journal ethics. J Public Health Policy. 2018 Jun 8. PMID: 29884897

Torretta V, Katsoyiannis IA, Viotti P and Rada EC. Critical Review of the Effects of Glyphosate Exposure to the Environment and Humans through the Food Supply Chain. 2018 Mar 24. Sustainability 2018, 10, 950.

Huhn C. More and enhanced glyphosate analysis is needed. Anal Bioanal Chem. 2018 May;410(13):3041-3045.PMID: 29552731

Duke SO. The history and current status of glyphosate. Pest Manag Sci. 2018 May;74(5):1027-1034. PMID: 28643882

Mertens M, Höss S, Neumann G, Afzal J, Reichenbecher W. Glyphosate, a chelating agent-relevant for ecological risk assessment? Environ Sci Pollut Res Int. 2018 Feb;25(6):5298-5317. PMID: 29294235

Kniss AR. Long-term trends in the intensity and relative toxicity of herbicide use. Nat Commun. 2017 Apr 10;8:14865. PMID: 28393866

Mesnage R, Antoniou MN. Facts and Fallacies in the Debate on Glyphosate Toxicity. Front Public Health. 2017 Nov 24;5:316.  PMID: 292261

Vandenberg LN, Blumberg B, Antoniou MN, Benbrook CM, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP, Mesnage R, Vom Saal FS, Welshons WV, Myers JP. Is it time to reassess current safety standards for glyphosate-based herbicides? J Epidemiol Community Health. 2017 Jun;71(6):613-618. PMID: 28320775

Benbrook CM. Trends in glyphosate herbicide use in the United States and globally. Environ Sci Eur. 2016;28(1):3. PMID: 27752438

 

Overall Health Effects

Jiang X, Zhang N, Yin L, Zhang WL, Han F, Liu WB, Chen HQ, Cao J, Liu JY. A commercial Roundup formulation induced male germ cell apoptosis by promoting the expression of XAF1 in adult mice. Toxicol Lett. 2018 Jun 15. PMID: 29908847

Cho YS, Moon JM, Chun BJ, Lee BK. Use of Qsofa Score in Predicting the Outcomes of Patients with Glyphosate Surfactant Herbicide Poisoning Immediately Upon Arrival at the Emergency Department. Shock. 2018 Jun 8. PMID: 29889814

Panzacchi S, Mandrioli D, Manservisi F, Bua L, Falcioni L, Spinaci M, Galeati G, Dinelli G, Miglio R, Mantovani A, Lorenzetti S, Hu J, Chen J, Perry MJ, Landrigan PJ, Belpoggi F. The Ramazzini Institute 13-week study on glyphosate-based herbicides at human-equivalent dose in Sprague Dawley rats: study design and first in-life endpoints evaluation. Environ Health. 2018 May 29;17(1):52. PMID: 29843719

Altamirano GA, Delconte MB, Gomez AL, Ingaramo PI, Bosquiazzo VL, Luque EH, Muñoz-de-Toro M, Kass L. Postnatal exposure to a glyphosate-based herbicide modifies mammary gland growth and development in Wistar male rats. Food Chem Toxicol. 2018 May 7;118:111-118. PMID: 29746933

Xie Z, Zou S, Xu W, Liu X, Huang K, He X. No subchronic toxicity of multiple herbicide-resistant soybean FG72 in Sprague-Dawley rats by 90-days feeding study. Regul Toxicol Pharmacol. 2018 Apr;94:299-305. PMID: 29462651

Good P. Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). Clin Nutr ESPEN. 2018 Feb;23:171-183. PMID: 29460795

Picetti E, Generali M, Mensi F, Neri G, Damia R, Lippi G, Cervellin G. Glyphosate ingestion causing multiple organ failure: a near-fatal case report. Acta Biomed. 2018 Jan 16;88(4):533-537. PMID: 29350673

Defarge N, Spiroux de Vendômois J, Séralini GE. Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides. Toxicol Rep. 2017 Dec 30;5:156-163. PMID: 29321978

Van Bruggen AHC, He MM, Shin K, Mai V, Jeong KC, Finckh MR, Morris JG Jr. Environmental and health effects of the herbicide glyphosate. Sci Total Environ. 2018 Mar;616-617:255-268. PMID: 29117584

Schnabel K, Schmitz R, von Soosten D, Frahm J, Kersten S, Meyer U, Breves G, Hackenberg R, Spitzke M, Dänicke S. Effects of glyphosate residues and different concentrate feed proportions on performance, energy metabolism and health characteristics in lactating dairy cows. Arch Anim Nutr. 2017 Dec;71(6):413-427. PMID: 29110579

Baier CJ, Gallegos CE, Raisman-Vozari R, Minetti A. Behavioral impairments following repeated intranasal glyphosate-based herbicide administration in mice. Neurotoxicol Teratol. 2017 Nov;64:63-72. PMID: 29061523

Perego MC, Caloni F, Cortinovis C, Schutz LF, Albonico M, Tsuzukibashi D, Spicer LJ. Influence of a Roundup formulation on glyphosate effects on steroidogenesis and proliferation of bovine granulosa cells in vitro. Chemosphere. 2017 Dec;188:274-279. PMID: 28888115

Ait Bali Y, Ba-Mhamed S, Bennis M. Behavioral and Immunohistochemical Study of the Effects of Subchronic and Chronic Exposure to Glyphosate in Mice. Front Behav Neurosci. 2017 Aug 8;11:146. PMID: 28848410

de Ávila RI, Teixeira GC, Veloso DFMC, Moreira LC, Lima EM, Valadares MC. In vitro assessment of skin sensitization, photosensitization and phototoxicity potential of commercial glyphosate-containing formulations. Toxicol In Vitro. 2017 Dec;45(Pt 3):386-392. PMID: 28389279

Bai SH, Ogbourne SM. Glyphosate: environmental contamination, toxicity and potential risks to human health via food contamination. Environ Sci Pollut Res Int. 2016 Oct;23(19):18988-9001. PMID: 27541149

Hoppin JA, Umbach DM, Long S, London SJ, Henneberger PK, Blair A, Alavanja M, Freeman LE, Sandler DP. Pesticides are Associated with Allergic and Non-Allergic Wheeze among Male Farmers. Environ Health Perspect. 2017 Apr;125(4):535-543. PMID: 27384423

Kwiatkowska M, Jarosiewicz P, Michałowicz J, Koter-Michalak M, Huras B, Bukowska B. The Impact of Glyphosate, Its Metabolites and Impurities on Viability, ATP Level and Morphological changes in Human Peripheral Blood Mononuclear Cells. PLoS One. 2016 Jun 9;11(6):e0156946. PMID: 27280764

Martini CN, Gabrielli M, Brandani JN, Vila Mdel C. Glyphosate Inhibits PPAR Gamma Induction and Differentiation of Preadipocytes and is able to Induce Oxidative Stress. J Biochem Mol Toxicol. 2016 Aug;30(8):404-13. PMID: 27044015

Morris A, Murrell EG, Klein T, Noden BH. Effect of two commercial herbicides on life history traits of a human disease vector, Aedes aegypti, in the laboratory setting. Ecotoxicology. 2016 Jul;25(5):863-70. PMID: 26965703

Myers JP, Antoniou MN, Blumberg B, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP, Mesnage R, Vandenberg LN, Vom Saal FS, Welshons WV, Benbrook CM. Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. Environ Health. 2016 Feb 17;15:19. PMID: 26883814

Xu J, Li G, Wang Z, Si L, He S, Cai J, Huang J, Donovan MD. The role of L-type amino acid transporters in the uptake of glyphosate across mammalian epithelial tissues. Chemosphere. 2016 Feb;145:487-94. PMID: 26701683

Caloni F, Cortinovis C, Rivolta M, Davanzo F. Suspected poisoning of domestic animals by pesticides. Sci Total Environ. 2016 Jan 1;539:331-336. PMID: 26367188

Mesnage R, Defarge N, Spiroux de Vendômois J, Séralini GE. Potential toxic effects of glyphosate and its commercial formulations below regulatory limits. Food Chem Toxicol. 2015 Oct;84:133-53. PMID: 26282372

De Raadt WM, Wijnen PA, Bast A, Bekers O, Drent M. Acute eosinophilic pneumonia associated with glyphosate-surfactant exposure. Sarcoidosis Vasc Diffuse Lung Dis. 2015 Jul 22;32(2):172-5. PMID: 26278698

Thakur DS, Khot R, Joshi PP, Pandharipande M, Nagpure K. Glyphosate poisoning with acute pulmonary edema. Toxicol Int. 2014 Sep-Dec;21(3):328-30. PMID: 25948977

Cortinovis C, Davanzo F, Rivolta M, Caloni F. Glyphosate-surfactant herbicide poisoning in domestic animals: an epidemiological survey. Vet Rec. 2015 Apr 18;176(16):413. PMID: 25672343

He S, Tang G. The review of study on glyphosate hebicide toxic effects. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2014 Nov;32(11):868-71. PMID: 25579045

Tizhe EV, Ibrahim ND, Fatihu MY, Onyebuchi II, George BD, Ambali SF, Shallangwa JM. Influence of zinc supplementation on histopathological changes in the stomach, liver, kidney, brain, pancreas and spleen during subchronic exposure of Wistar rats to glyphosate. Comp Clin Path. 2014;23(5):1535-1543. PMID: 25258622

Kwiatkowska M, Nowacka-Krukowska H, Bukowska B. The effect of glyphosate, its metabolites and impurities on erythrocyte acetylcholinesterase activity. Environ Toxicol Pharmacol. 2014 May;37(3):1101-8. PMID: 24780534

Campbell AW. Glyphosate: its effects on humans. Altern Ther Health Med. 2014 May-Jun;20(3):9-11. PMID: 24755565

Garlich FM, Goldman M, Pepe J, Nelson LS, Allan MJ, Goldstein DA, Goldfarb DS, Hoffman RS. Hemodialysis clearance of glyphosate following a life-threatening ingestion of glyphosate-surfactant herbicide. Clin Toxicol (Phila). 2014 Jan;52(1):66-71. PMID: 24400933

Bates N, Edwards N. Glyphosate toxicity in animals. Clin Toxicol (Phila). 2013 Dec;51(10):1243. PMID: 24138506

Olszyk D, Blakeley-Smith M, Pfleeger T, Lee EH, Plocher M. Effects of low levels of herbicides on prairie species of the Willamette Valley, Oregon. Environ Toxicol Chem. 2013 Nov;32(11):2542-51. PMID: 23881750

Jasper R, Locatelli GO, Pilati C, Locatelli C. Evaluation of biochemical, hematological and oxidative parameters in mice exposed to the herbicide glyphosate-Roundup. Interdiscip Toxicol. 2012 Sep;5(3):133-40. PMID: 23554553

Mariager TP, Madsen PV, Ebbehøj NE, Schmidt B, Juhl A. Severe adverse effects related to dermal exposure to a glyphosate-surfactant herbicide. Clin Toxicol (Phila). 2013 Feb;51(2):111-3. PMID: 23360343

Mesnage R, Bernay B, Séralini GE. Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity. Toxicology. 2013 Nov 16;313(2-3):122-8. PMID: 23000283

Sribanditmongkol P, Jutavijittum P, Pongraveevongsa P, Wunnapuk K, Durongkadech P. Pathological and toxicological findings in glyphosate-surfactant herbicide fatality: a case report. Am J Forensic Med Pathol. 2012 Sep;33(3):234-7. PMID: 22835958

Song HY, Kim YH, Seok SJ, Gil HW, Hong SY. In vitro cytotoxic effect of glyphosate mixture containing surfactants. J Korean Med Sci. 2012 Jul;27(7):711-5. PMID: 22787363

Gui YX, Fan XN, Wang HM, Wang G, Chen SD. Glyphosate induced cell death through apoptotic and autophagic mechanisms. Neurotoxicol Teratol. 2012 May-Jun;34(3):344-9. PMID: 22504123

Mesnage R, Clair E, Gress S, Then C, Székács A, Séralini GE. Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins alone or with a glyphosate-based herbicide. J Appl Toxicol. 2013 Jul;33(7):695-9. PMID: 22337346

Seok SJ, Park JS, Hong JR, Gil HW, Yang JO, Lee EY, Song HY, Hong SY. Surfactant volume is an essential element in human toxicity in acute glyphosate herbicide intoxication. Clin Toxicol (Phila). 2011 Dec;49(10):892-9. PMID: 22077202

Mink PJ, Mandel JS, Lundin JI, Sceurman BK. Epidemiologic studies of glyphosate and non-cancer health outcomes: a review. Regul Toxicol Pharmacol. 2011 Nov;61(2):172-84. PMID: 21798302

Alvarez-Moya C, Silva MR, Arámbula AR, Sandoval AI, Vasquez HC, González Montes RM. Evaluation of genetic damage induced by glyphosate isopropylamine salt using Tradescantia bioassays. Genet Mol Biol. 2011 Jan;34(1):127-30. PMID: 21637555

Varona M, Henao GL, Díaz S, Lancheros A, Murcia A, Rodríguez N, Alvarez VH. Effects of aerial applications of the herbicide glyphosate and insecticides on human health. Biomedica. 2009 Sep;29(3):456-75. PMID: 20436997

El-Shenawy NS. Oxidative stress responses of rats exposed to Roundup and its active ingredient glyphosate. Environ Toxicol Pharmacol. 2009 Nov;28(3):379-85. PMID: 21784030

Solomon KR, Marshall EJ, Carrasquilla G. Human health and environmental risks from the use of glyphosate formulations to control the production of coca in Colombia: overview and conclusions. J Toxicol Environ Health A. 2009;72(15-16):914-20. PMID: 19672759

Lee HL, Kan CD, Tsai CL, Liou MJ, Guo HR. Comparative effects of the formulation of glyphosate-surfactant herbicides on hemodynamics in swine. Clin Toxicol (Phila). 2009 Aug;47(7):651-8. PMID: 19663613

Chen YJ, Wu ML, Deng JF, Yang CC. The epidemiology of glyphosate-surfactant herbicide poisoning in Taiwan, 1986-2007: a poison center study. Clin Toxicol (Phila). 2009 Aug;47(7):670-7. PMID: 19640238

Anadón A, Martínez-Larrañaga MR, Martínez MA, Castellano VJ, Martínez M, Martin MT, Nozal MJ, Bernal JL. Toxicokinetics of glyphosate and its metabolite aminomethyl phosphonic acid in rats. Toxicol Lett. 2009 Oct 8;190(1):91-5. PMID: 19607892

Appenzeller LM, Munley SM, Hoban D, Sykes GP, Malley LA, Delaney B. Subchronic feeding study of grain from herbicide-tolerant maize DP-Ø9814Ø-6 in Sprague-Dawley rats. Food Chem Toxicol. 2009 Sep;47(9):2269-80. PMID: 19524635

Astiz M, de Alaniz MJ, Marra CA. Effect of pesticides on cell survival in liver and brain rat tissues. Ecotoxicol Environ Saf. 2009 Oct;72(7):2025-32. PMID: 19493570

Benachour N, Séralini GE. Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. Chem Res Toxicol. 2009 Jan;22(1):97-105. PMID: 19105591

Martínez A, Reyes I, Reyes N. Cytotoxicity of the herbicide glyphosate in human peripheral blood mononuclear cells. Biomedica. 2007 Dec;27(4):594-604. Spanish. PMID: 18320126

Cağlar S, Kolankaya D. The effect of sub-acute and sub-chronic exposure of rats to the glyphosate-based herbicide Roundup. Environ Toxicol Pharmacol. 2008 Jan;25(1):57-62. PMID: 21783836

 

Microbiome

 Kurenbach B, Gibson PS, Hill AM, Bitzer AS, Silby MW, Godsoe W, Heinemann JA. Herbicide ingredients change Salmonella enterica sv. Typhimurium and Escherichia coli antibiotic responses. Microbiology. 2017 Nov 17. PMID: 29139345

Nielsen LN, Roager HM, Casas ME, Frandsen HL, Gosewinkel U, Bester K, Licht TR, Hendriksen NB, Bahl MI. Glyphosate has limited short-term effects on commensal bacterial community composition in the gut environment due to sufficient aromatic amino acid levels. Environ Pollut. 2018 Feb;233:364-376. PMID: 29096310

Mao Q, Manservisi F, Panzacchi S, Mandrioli D, Menghetti I, Vornoli A, Bua L, Falcioni L, Lesseur C, Chen J, Belpoggi F, Hu J. The Ramazzini Institute 13-week pilot study on glyphosate and Roundup administered at human-equivalent dose to Sprague Dawley rats: effects on the microbiome. Environ Health. 2018 May 29;17(1):50. PMID: 29843725

Aitbali Y, Ba-M’hamed S, Elhidar N, Nafis A, Soraa N, Bennis M. Glyphosate based- herbicide exposure affects gut microbiota, anxiety and depression-like behaviors in mice. Neurotoxicol Teratol. 2018 May – Jun;67:44-49. PMID: 29635013

Lozano VL, Defarge N, Rocque LM, Mesnage R, Hennequin D, Cassier R, de Vendômois JS, Panoff JM, Séralini GE, Amiel C. Sex-dependent impact of Roundup on the rat gut microbiome. Toxicol Rep. 2017 Dec 19;5:96-107. PMID: 29854581

Ackermann W, Coenen M, Schrödl W, Shehata AA, Krüger M. The influence of glyphosate on the microbiota and production of botulinum neurotoxin during ruminal fermentation. Curr Microbiol. 2015 Mar;70(3):374-82. PMID: 25407376

Schrödl W, Krüger S, Konstantinova-Müller T, Shehata AA, Rulff R, Krüger M. Possible effects of glyphosate on Mucorales abundance in the rumen of dairy cows in Germany. Curr Microbiol. 2014 Dec;69(6):817-23. PMID: 25079171

Shehata AA, Schrödl W, Aldin AA, Hafez HM, Krüger M. The effect of glyphosate on potential pathogens and beneficial members of poultry microbiota in vitro. Curr Microbiol. 2013 Apr;66(4):350-8. PMID: 23224412

 

Reproductive

Milesi MM, Lorenz V, Pacini G, Repetti MR, Demonte LD, Varayoud J, Luque EH. Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats. Arch Toxicol. 2018 Jun 9. PMID: 29947892

Bonvallot N, Canlet C, Blas-Y-Estrada F, Gautier R, Tremblay-Franco M, Chevolleau S, Cordier S, Cravedi JP. Metabolome disruption of pregnant rats and their offspring resulting from repeated exposure to a pesticide mixture representative of environmental contamination in Brittany. PLoS One. 2018 Jun 20;13(6):e0198448. PMID: 29924815

Gigante P, Berni M, Bussolati S, Grasselli F, Grolli S, Ramoni R, Basini G. Glyphosate affects swine ovarian and adipose stromal cell functions. Anim Reprod Sci. 2018 May 24. pii: S0378-4320(17)31046-1. PMID: 29843941

Anifandis G, Katsanaki K, Lagodonti G, Messini C, Simopoulou M, Dafopoulos K, Daponte A. The Effect of Glyphosate on Human Sperm Motility and Sperm DNA Fragmentation. Int J Environ Res Public Health. 2018 May 30;15(6). PMID: 29848988

Landrigan PJ, Belpoggi F. The need for independent research on the health effects of glyphosate-based herbicides. Environ Health. 2018 May 29;17(1):51. PMID: 29843729

Avdatek F, Birdane YO, Türkmen R, Demirel HH. Ameliorative effect of resveratrol on testicular oxidative stress, spermatological parameters and DNA damage in glyphosate-based herbicide-exposed rats. Andrologia. 2018 May 14:e13036. PMID: 29761542

Parvez S, Gerona RR, Proctor C, Friesen M, Ashby JL, Reiter JL, Lui Z, Winchester PD. Glyphosate exposure in pregnancy and shortened gestational length: a prospective Indiana birth cohort study. Environ Health. 2018 Mar 9;17(1):23. PMID: 29519238

Ji H, Xu L, Wang Z, Fan X, Wu L. Differential microRNA expression in the prefrontal cortex of mouse offspring induced by glyphosate exposure during pregnancy and lactation. Exp Ther Med. 2018 Mar;15(3):2457-2467. PMID: 29467848

Anifandis G, Amiridis G, Dafopoulos K, Daponte A, Dovolou E, Gavriil E, Gorgogietas V, Kachpani E, Mamuris Z, Messini CI, Vassiou K, Psarra AG. The In Vitro Impact of the Herbicide Roundup on Human Sperm Motility and Sperm Mitochondria. Toxics. 2017 Dec 21;6(1). PMID: 29267194

Cai W, Ji Y, Song X, Guo H, Han L, Zhang F, Liu X, Zhang H, Zhu B, Xu M. Effects of glyphosate exposure on sperm concentration in rodents: A systematic review and meta-analysis. Environ Toxicol Pharmacol. 2017 Oct;55:148-155. PMID: 28846991

Owagboriaye FO, Dedeke GA, Ademolu KO, Olujimi OO, Ashidi JS, Adeyinka AA. Reproductive toxicity of Roundup herbicide exposure in male albino rat. Exp Toxicol Pathol. 2017 Sep 5;69(7):461-468. PMID: 28473188

Perego MC, Schutz LF, Caloni F, Cortinovis C, Albonico M, Spicer LJ. Evidence for direct effects of glyphosate on ovarian function: glyphosate influences steroidogenesis and proliferation of bovine granulosa but not theca cells in vitro. J Appl Toxicol. 2017 Jun;37(6):692-698. PMID: 27917511

Varayoud J, Durando M, Ramos JG, Milesi MM, Ingaramo PI, Muñoz-de-Toro M, Luque EH. Effects of a glyphosate-based herbicide on the uterus of adult ovariectomized rats. Environ Toxicol. 2017 Apr;32(4):1191-1201. PMID: 27463640

Dai P, Hu P, Tang J, Li Y, Li C. Effect of glyphosate on reproductive organs in male rat. Acta Histochem. 2016 Jun;118(5):519-26. PMID: 27286640

de Araujo JS, Delgado IF, Paumgartten FJ. Glyphosate and adverse pregnancy outcomes, a systematic review of observational studies. BMC Public Health. 2016 Jun 6;16:472. PMID: 27267204

Abarikwu SO, Akiri OF, Durojaiye MA, Adenike A. Combined effects of repeated administration of Bretmont Wipeout (glyphosate) and Ultrazin (atrazine) on testosterone, oxidative stress and sperm quality of Wistar rats. Toxicol Mech Methods. 2015 Jan;25(1):70-80. PMID: 25403740

Cassault-Meyer E, Gress S, Séralini GÉ, Galeraud-Denis I. An acute exposure to glyphosate-based herbicide alters aromatase levels in testis and sperm nuclear quality. Environ Toxicol Pharmacol. 2014 Jul;38(1):131-40. PMID: 24930125

de Liz Oliveira Cavalli VL, Cattani D, Heinz Rieg CE, Pierozan P, Zanatta L, Benedetti Parisotto E, Wilhelm Filho D, Mena Barreto Silva FR, Pessoa-Pureur R, Zamoner A. Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells. Free Radic Biol Med. 2013 Dec;65:335-46. PMID: 23820267

Astiz M, Hurtado de Catalfo GE, García MN, Galletti SM, Errecalde AL, de Alaniz MJ, Marra CA. Pesticide-induced decrease in rat testicular steroidogenesis is differentially prevented by lipoate and tocopherol. Ecotoxicol Environ Saf. 2013 May;91:129-38. PMID: 23465731

Williams AL, Watson RE, DeSesso JM. Developmental and reproductive outcomes in humans and animals after glyphosate exposure: a critical analysis. J Toxicol Environ Health B Crit Rev. 2012;15(1):39-96. PMID: 22202229

Clair E, Mesnage R, Travert C, Séralini GÉ. A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels. Toxicol In Vitro. 2012 Mar;26(2):269-79. PMID: 22200534

Romano MA, Romano RM, Santos LD, Wisniewski P, Campos DA, de Souza PB, Viau P, Bernardi MM, Nunes MT, de Oliveira CA. Glyphosate impairs male offspring reproductive development by disrupting gonadotropin expression. Arch Toxicol. 2012 Apr;86(4):663-73. PMID: 22120950

Romano RM, Romano MA, Bernardi MM, Furtado PV, Oliveira CA. Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology. Arch Toxicol. 2010 Apr;84(4):309-17. PMID: 20012598

Sanin LH, Carrasquilla G, Solomon KR, Cole DC, Marshall EJ. Regional differences in time to pregnancy among fertile women from five Colombian regions with different use of glyphosate. J Toxicol Environ Health A. 2009;72(15-16):949-60. PMID: 19672763

 

Neonatal Exposures

Ingaramo PI, Varayoud J, Milesi MM, Guerrero Schimpf M, Alarcón R, Muñoz-de-Toro M, Luque EH. Neonatal exposure to a glyphosate-based herbicide alters uterine decidualization in rats. Reprod Toxicol. 2017 Oct;73:87-95. PMID: 28780397

Cattani D, Cesconetto PA, Tavares MK, Parisotto EB, De Oliveira PA, Rieg CEH, Leite MC, Prediger RDS, Wendt NC, Razzera G, Filho DW, Zamoner A. Developmental exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative stress. Toxicology. 2017 Jul 15;387:67-80. PMID: 28627408

de Souza JS, Kizys MM, da Conceição RR, Glebocki G, Romano RM, Ortiga-Carvalho TM, Giannocco G, da Silva ID, Dias da Silva MR, Romano MA, Chiamolera MI. Perinatal exposure to glyphosate-based herbicide alters the thyrotrophic axis and causes thyroid hormone homeostasis imbalance in male rats. Toxicology. 2017 Feb 15;377:25-37. PMID: 27916585

Almeida LL, Teixeira ÁAC, Soares AF, Cunha FMD, Silva VAD Júnior, Vieira Filho LD, Wanderley-Teixeira V. Effects of melatonin in rats in the initial third stage of pregnancy exposed to sub-lethal doses of herbicides. Acta Histochem. 2017 Apr;119(3):220-227. PMID: 28202179

Guerrero Schimpf M, Milesi MM, Ingaramo PI, Luque EH, Varayoud J. Neonatal exposure to a glyphosate based herbicide alters the development of the rat uterus. Toxicology. 2017 Feb 1;376:2-14. PMID: 27287056

Ingaramo PI, Varayoud J, Milesi MM, Schimpf MG, Muñoz-de-Toro M, Luque EH. Effects of neonatal exposure to a glyphosate-based herbicide on female rat reproduction. Reproduction. 2016 Nov;152(5):403-15. PMID: 27486271

Gallegos CE, Bartos M, Bras C, Gumilar F, Antonelli MC, Minetti A. Exposure to a glyphosate-based herbicide during pregnancy and lactation induces neurobehavioral alterations in rat offspring. Neurotoxicology. 2016 Mar;53:20-28. PMID: 26632987

Mose T, Kjaerstad MB, Mathiesen L, Nielsen JB, Edelfors S, Knudsen LE. Placental passage of benzoic acid, caffeine, and glyphosate in an ex vivo human perfusion system. J Toxicol Environ Health A. 2008;71(15):984-91. PMID: 18569607

Dallegrave E, Mantese FD, Oliveira RT, Andrade AJ, Dalsenter PR, Langeloh A. Pre- and postnatal toxicity of the commercial glyphosate formulation in Wistar rats. Arch Toxicol. 2007 Sep;81(9):665-73. PMID: 17634926

 

Cancer

Ward EM. Glyphosate Use and Cancer Incidence in the Agricultural Health Study: An Epidemiologic Perspective. J Natl Cancer Inst. 2018 May 1;110(5):446-447. PMID: 29155945

Andreotti G, Koutros S, Hofmann JN, Sandler DP, Lubin JH, Lynch CF, Lerro CC, De Roos AJ, Parks CG, Alavanja MC, Silverman DT, Beane Freeman LE. Glyphosate Use and Cancer Incidence in the Agricultural Health Study. J Natl Cancer Inst. 2018 May 1;110(5):509-516. PMID: 29136183

Sritana N, Suriyo T, Kanitwithayanun J, Songvasin BH, Thiantanawat A, Satayavivad J. Glyphosate induces growth of estrogen receptor alpha positive cholangiocarcinoma cells via non-genomic estrogen receptor/ERK1/2 signaling pathway. Food Chem Toxicol. 2018 Jun 8;118:595-607.PMID: 29890199

Tarazona JV, Court-Marques D, Tiramani M, Reich H, Pfeil R, Istace F, Crivellente F. Glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC. Arch Toxicol. 2017 Aug;91(8):2723-2743. PMID: 28374158

Bus JS. IARC use of oxidative stress as key mode of action characteristic for facilitating cancer classification: Glyphosate case example illustrating a lack of robustness in interpretative implementation. Regul Toxicol Pharmacol. 2017 Jun;86:157-166. PMID: 28274811

Williams GM, Berry C, Burns M, de Camargo JL, Greim H. Glyphosate rodent carcinogenicity bioassay expert panel review. Crit Rev Toxicol. 2016 Sep;46(sup1):44-55. PMID: 27677669

Acquavella J, Garabrant D, Marsh G, Sorahan T, Weed DL. Glyphosate epidemiology expert panel review: a weight of evidence systematic review of the relationship between glyphosate exposure and non-Hodgkin’s lymphoma or multiple myeloma. Crit Rev Toxicol. 2016 Sep;46(sup1):28-43. PMID: 27677668

Chang ET, Delzell E. Systematic review and meta-analysis of glyphosate exposure and risk of lymphohematopoietic cancers. J Environ Sci Health B. 2016;51(6):402-34. PMID: 27015139

Malagoli C, Costanzini S, Heck JE, Malavolti M, De Girolamo G, Oleari P, Palazzi G, Teggi S, Vinceti M. Passive exposure to agricultural pesticides and risk of childhood leukemia in an Italian community. Int J Hyg Environ Health. 2016 Nov;219(8):742-748. PMID: 27693118

Portier CJ, Armstrong BK, Baguley BC, Baur X, Belyaev I, Bellé R, Belpoggi F, Biggeri A, Bosland MC, Bruzzi P, Budnik LT, Bugge MD, Burns K, Calaf GM, Carpenter DO, Carpenter HM, López-Carrillo L, Clapp R, Cocco P, Consonni D, Comba P, Craft E, Dalvie MA, Davis D, Demers PA, De Roos AJ, DeWitt J, Forastiere F, Freedman JH, Fritschi L, Gaus C, Gohlke JM, Goldberg M, Greiser E, Hansen J, Hardell L, Hauptmann M, Huang W, Huff J, James MO, Jameson CW, Kortenkamp A, Kopp-Schneider A, Kromhout H, Larramendy ML, Landrigan PJ, Lash LH, Leszczynski D, Lynch CF, Magnani C, Mandrioli D, Martin FL, Merler E, Michelozzi P, Miligi L, Miller AB, Mirabelli D, Mirer FE, Naidoo S, Perry MJ, Petronio MG, Pirastu R, Portier RJ, Ramos KS, Robertson LW, Rodriguez T, Röösli M, Ross MK, Roy D, Rusyn I, Saldiva P, Sass J, Savolainen K, Scheepers PT, Sergi C, Silbergeld EK, Smith MT, Stewart BW, Sutton P, Tateo F, Terracini B, Thielmann HW, Thomas DB, Vainio H, Vena JE, Vineis P, Weiderpass E, Weisenburger DD, Woodruff TJ, Yorifuji T, Yu IJ, Zambon P, Zeeb H, Zhou SF. Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA). J Epidemiol Community Health. 2016 Aug;70(8):741-5. PMID: 26941213

Williams GM, Aardema M, Acquavella J, Berry SC, Brusick D, Burns MM, de Camargo JL, Garabrant D, Greim HA, Kier LD, Kirkland DJ, Marsh G, Solomon KR, Sorahan T, Roberts A, Weed DL. A review of the carcinogenic potential of glyphosate by four independent expert panels and comparison to the IARC assessment. Crit Rev Toxicol. 2016 Sep;46(sup1):3-20. PMID: 27677666

Parajuli KR, Zhang Q, Liu S, You Z. Aminomethylphosphonic acid and methoxyacetic acid induce apoptosis in prostate cancer cells. Int J Mol Sci. 2015 May 22;16(5):11750-65. PMID: 26006246

Guyton KZ, Loomis D, Grosse Y, El Ghissassi F, Benbrahim-Tallaa L, Guha N, Scoccianti C, Mattock H, Straif K; International Agency for Research on Cancer Monograph Working Group, IARC, Lyon, France. Carcinogenicity of tetrachlorvinphos, parathion, malathion, diazinon, and glyphosate. Lancet Oncol. 2015 May;16(5):490-1. PMID: 25801782

Sorahan, T. Multiple Myeloma and Glyphosate Use: A Re-Analysis of US Agricultural Health Study (AHS) Data. Int. J. Environ. Res. Public Health 2015, 12, 1548-1559. PMID: 25635915

Greim H, Saltmiras D, Mostert V, Strupp C. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015 Mar;45(3):185-208. PMID: 25716480

Schinasi L, Leon ME. Non-Hodgkin lymphoma and occupational exposure to agricultural pesticide chemical groups and active ingredients: a systematic review and meta-analysis. Int J Environ Res Public Health. 2014 Apr 23;11(4):4449-527. PMID: 24762670

Thongprakaisang S, Thiantanawat A, Rangkadilok N, Suriyo T, Satayavivad J. Glyphosate induces human breast cancer cells growth via estrogen receptors. Food Chem Toxicol. 2013 Sep;59:129-36. PMID: 23756170

Mink PJ, Mandel JS, Sceurman BK, Lundin JI. Epidemiologic studies of glyphosate and cancer: a review. Regul Toxicol Pharmacol. 2012 Aug;63(3):440-52. PMID: 22683395

Eriksson M, Hardell L, Carlberg M, Akerman M. Pesticide exposure as risk factor for non-Hodgkin lymphoma including histopathological subgroup analysis. Int J Cancer. 2008 Oct 1;123(7):1657-63. PMID: 18623080

 

Kidneys & Liver

Dedeke GA, Owagboriaye FO, Ademolu KO, Olujimi OO, Aladesida AA. Comparative Assessment on Mechanism Underlying Renal Toxicity of Commercial Formulation of Roundup Herbicide and Glyphosate Alone in Male Albino Rat. Int J Toxicol. 2018 Jan 1:1091581818779553. PMID: 29890881

Gunarathna S, Gunawardana B, Jayaweera M, Manatunge J, Zoysa K. Glyphosate and AMPA of agricultural soil, surface water, groundwater and sediments in areas prevalent with chronic kidney disease of unknown etiology, Sri Lanka. J Environ Sci Health B. 2018 Jun 8:1-9. PMID: 29883246

Tang J, Hu P, Li Y, Win-Shwe TT, Li C. Ion Imbalance Is Involved in the Mechanisms of Liver Oxidative Damage in Rats Exposed to Glyphosate. Front Physiol. 2017 Dec 19;8:1083. PMID: 29311996

Kašuba V, Milić M, Rozgaj R, Kopjar N, Mladinić M, Žunec S, Vrdoljak AL, Pavičić I, Čermak AMM, Pizent A, Lovaković BT, Želježić D. Effects of low doses of glyphosate on DNA damage, cell proliferation and oxidative stress in the HepG2 cell line. Environ Sci Pollut Res Int. 2017 Aug;24(23):19267-19281. PMID: 28667585

Indirakshi J, Sunnesh A, Aruna M, Reddy MH, Kumar AC, Chandra VS, Sangeetha B, Katyarmal DT, Ram R, Kumar VS. Toxic Epidermal Necrolysis and Acute Kidney Injury due to Glyphosate Ingestion. Indian J Crit Care Med. 2017 Mar;21(3):167-169. PMID: 28400689

Luo L, Wang F, Zhang Y, Zeng M, Zhong C, Xiao F. In vitro cytotoxicity assessment of roundup (glyphosate) in L-02 hepatocytes. J Environ Sci Health B. 2017 Jun 3;52(6):410-417. PMID: 28281894

Mesnage R, Arno M, Séralini GE, Antoniou MN. Transcriptome and metabolome analysis of liver and kidneys of rats chronically fed NK603 Roundup-tolerant genetically modified maize. Environ Sci Eur. 2017;29(1):6. PMID: 28239534

Mesnage R, Renney G, Séralini GE, Ward M, Antoniou MN. Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide. Sci Rep. 2017 Jan 9;7:39328. PMID: 28067231

Mesnage R, Arno M, Costanzo M, Malatesta M, Séralini GE, Antoniou MN. Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure. Environ Health. 2015 Aug 25;14:70. PMID: 26302742

Jayasumana C, Gunatilake S, Siribaddana S. Simultaneous exposure to multiple heavy metals and glyphosate may contribute to Sri Lankan agricultural nephropathy. BMC Nephrol. 2015 Jul 11;16:103. PMID: 26162605

Tizhe EV, Ibrahim ND, Fatihu MY, Igbokwe IO, George BD, Ambali SF, Shallangwa JM. Serum biochemical assessment of hepatic and renal functions of rats during oral exposure to glyphosate with zinc. Comp Clin Path. 2014;23:1043-1050. PMID: 25067936

Jayasumana C, Gunatilake S, Senanayake P. Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in Sri Lanka? Int J Environ Res Public Health. 2014 Feb 20;11(2):2125-47. PMID: 24562182

Wunnapuk K, Gobe G, Endre Z, Peake P, Grice JE, Roberts MS, Buckley NA, Liu X. Use of a glyphosate-based herbicide-induced nephrotoxicity model to investigate a panel of kidney injury biomarkers. Toxicol Lett. 2014 Feb 10;225(1):192-200. PMID: 24361898

Malatesta M, Perdoni F, Santin G, Battistelli S, Muller S, Biggiogera M. Hepatoma tissue culture (HTC) cells as a model for investigating the effects of low concentrations of herbicide on cell structure and function. Toxicol In Vitro. 2008 Dec;22(8):1853-60. PMID: 18835430

 

Cardiovascular

Moon JM, Chun BJ, Cho YS, Lee SD, Hong YJ, Shin MH, Jung EJ, Ryu HH. Cardiovascular Effects and Fatality May Differ According to the Formulation of Glyphosate Salt Herbicide. Cardiovasc Toxicol. 2018 Feb;18(1):99-107. PMID: 28612304

Gress S, Lemoine S, Puddu PE, Séralini GE, Rouet R. Cardiotoxic Electrophysiological Effects of the Herbicide Roundup in Rat and Rabbit Ventricular Myocardium In Vitro. Cardiovasc Toxicol. 2015 Oct;15(4):324-35. PMID: 25448876

Gress S, Lemoine S, Séralini GE, Puddu PE. Glyphosate-based herbicides potently affect cardiovascular system in mammals: review of the literature. Cardiovasc Toxicol. 2015 Apr;15(2):117-26. PMID: 25245870

Kim YH, Lee JH, Hong CK, Cho KW, Park YH, Kim YW, Hwang SY. Heart rate-corrected QT interval predicts mortality in glyphosate-surfactant herbicide-poisoned patients. Am J Emerg Med. 2014 Mar;32(3):203-7. PMID: 24360317

Kimmel GL, Kimmel CA, Williams AL, DeSesso JM. Evaluation of developmental toxicity studies of glyphosate with attention to cardiovascular development. Crit Rev Toxicol. 2013 Feb;43(2):79-95. PMID: 23286529

You Y, Jung WJ, Lee MJ. Effect of intravenous fat emulsion therapy on glyphosate-surfactant-induced cardiovascular collapse. Am J Emerg Med. 2012 Nov;30(9):2097.e1-2. PMID: 22425001

Chang CB, Chang CC. Refractory cardiopulmonary failure after glyphosate surfactant intoxication: a case report. J Occup Med Toxicol. 2009 Jan 30;4:2. PMID: 191787554

 

Mitochondria

Pereira AG, Jaramillo ML, Remor AP, Latini A, Davico CE, da Silva ML, Müller YMR, Ammar D, Nazari EM. Low-concentration exposure to glyphosate-based herbicide modulates the complexes of the mitochondrial respiratory chain and induces mitochondrial hyperpolarization in the Danio rerio brain. Chemosphere. 2018 Jun 11;209:353-362. PMID: 29935464

Heu C, Elie-Caille C, Mougey V, Launay S, Nicod L. A step further toward glyphosate-induced epidermal cell death: involvement of mitochondrial and oxidative mechanisms. Environ Toxicol Pharmacol. 2012 Sep;34(2):144-153. PMID: 22522424

Bailey DC, Todt CE, Burchfield SL, Pressley AS, Denney RD, Snapp IB, Negga R, Traynor WL, Fitsanakis VA. Chronic exposure to a glyphosate-containing pesticide leads to mitochondrial dysfunction and increased reactive oxygen species production in Caenorhabditis elegans. Environ Toxicol Pharmacol. 2018 Jan;57:46-52. PMID: 29190595

 

Genotoxicity

Yu N, Tong Y, Zhang D, Zhao S, Fan X, Wu L, Ji H. Circular RNA expression profiles in hippocampus from mice with perinatal glyphosate exposure. Biochem Biophys Res Commun. 2018 Jul 2;501(4):838-845. PMID: 29705695

Townsend M, Peck C, Meng W, Heaton M, Robison R, O’Neill K. Evaluation of various glyphosate concentrations on DNA damage in human Raji cells and its impact on cytotoxicity. Regul Toxicol Pharmacol. 2017 Apr;85:79-85. PMID: 28185844

Kwiatkowska M, Reszka E, Woźniak K, Jabłońska E, Michałowicz J, Bukowska B. DNA damage and methylation induced by glyphosate in human peripheral blood mononuclear cells (in vitro study). Food Chem Toxicol. 2017 Jul;105:93-98. PMID: 28351773

Ford B, Bateman LA, Gutierrez-Palominos L, Park R, Nomura DK. Mapping Proteome-wide Targets of Glyphosate in Mice. Cell Chem Biol. 2017 Feb 16;24(2):133-140. PMID: 28132892

Kier LD. Review of genotoxicity biomonitoring studies of glyphosate-based formulations. Crit Rev Toxicol. 2015 Mar;45(3):209-18. PMID: 25687244

Kier LD, Kirkland DJ. Review of genotoxicity studies of glyphosate and glyphosate-based formulations. Crit Rev Toxicol. 2013 Apr;43(4):283-315. PMID: 23480780

Koller VJ, Fürhacker M, Nersesyan A, Mišík M, Eisenbauer M, Knasmueller S. Cytotoxic and DNA-damaging properties of glyphosate and Roundup in human-derived buccal epithelial cells. Arch Toxicol. 2012 May;86(5):805-13. PMID: 22331240

Guilherme S, Gaivão I, Santos MA, Pacheco M. European eel (Anguilla anguilla) genotoxic and pro-oxidant responses following short-term exposure to Roundup–a glyphosate-based herbicide. Mutagenesis. 2010 Sep;25(5):523-30. PMID: 20643706

Mladinic M, Berend S, Vrdoljak AL, Kopjar N, Radic B, Zeljezic D. Evaluation of genome damage and its relation to oxidative stress induced by glyphosate in human lymphocytes in vitro. Environ Mol Mutagen. 2009 Dec;50(9):800-7. PMID: 19402152

 

Neurological

Zhang C, Sun Y, Hu R, Huang J, Huang X, Li Y, Yin Y, Chen Z. A comparison of the effects of agricultural pesticide uses on peripheral nerve conduction in China. Sci Rep. 2018 Jun 25;8(1):9621. PMID: 29941882

Lafon PA, Imberdis T, Wang Y, Torrent J, Robitzer M, Huetter E, Alvarez-Martinez MT, Chevallier N, Givalois L, Desrumaux C, Liu J, Perrier V. Low doses of bioherbicide favour prion aggregation and propagation in vivo. Sci Rep. 2018 May 23;8(1):8023. PMID: 29795181

Gallegos CE, Baier CJ, Bartos M, Bras C, Domínguez S, Mónaco N, Gumilar F, Giménez MS, Minetti A. Perinatal Glyphosate-Based Herbicide Exposure in Rats Alters Brain Antioxidant Status, Glutamate and Acetylcholine Metabolism and Affects Recognition Memory. Neurotox Res. 2018 Apr 2.  PMID: 29611151

Martínez MA, Ares I, Rodríguez JL, Martínez M, Martínez-Larrañaga MR, Anadón A. Neurotransmitter changes in rat brain regions following glyphosate exposure. Environ Res. 2018 Feb;161:212-219. PMID: 29156344

Shaw W. Elevated Urinary Glyphosate and Clostridia Metabolites With Altered Dopamine Metabolism in Triplets With Autistic Spectrum Disorder or Suspected Seizure Disorder: A Case Study. Integr Med (Encinitas). 2017 Feb;16(1):50-57. PMID: 28223908

Kawagashira Y, Koike H, Kawabata K, Takahashi M, Ohyama K, Hashimoto R, Iijima M, Katsuno M, Sobue G. Vasculitic Neuropathy Following Exposure to a Glyphosate-based Herbicide. Intern Med. 2017;56(11):1431-1434. PMID: 28566611

Larsen KE, Lifschitz AL, Lanusse CE, Virkel GL. The herbicide glyphosate is a weak inhibitor of acetylcholinesterase in rats. Environ Toxicol Pharmacol. 2016 Jul;45:41-4. PMID: 27258137

Hernández-Plata I, Giordano M, Díaz-Muñoz M, Rodríguez VM. The herbicide glyphosate causes behavioral changes and alterations in dopaminergic markers in male Sprague-Dawley rat. Neurotoxicology. 2015 Jan;46:79-91. PMID: 25522657

Morley WA, Seneff S. Diminished brain resilience syndrome: A modern day neurological pathology of increased susceptibility to mild brain trauma, concussion, and downstream neurodegeneration. Surg Neurol Int. 2014 Jun 18;5:97. PMID: 25024897

Cattani D, de Liz Oliveira Cavalli VL, Heinz Rieg CE, Domingues JT, Dal-Cim T, Tasca CI, Mena Barreto Silva FR, Zamoner A. Mechanisms underlying the neurotoxicity induced by glyphosate-based herbicide in immature rat hippocampus: involvement of glutamate excitotoxicity. Toxicology. 2014 Jun 5;320:34-45. PMID: 24636977

Samsel A, Seneff S. Glyphosate, pathways to modern diseases III: Manganese, neurological diseases, and associated pathologies. Surg Neurol Int. 2015 Mar 24;6:45. PMID: 25883837

 

Endocrine

Nardi J, Moras PB, Koeppe C, Dallegrave E, Leal MB, Rossato-Grando LG. Prepubertal subchronic exposure to soy milk and glyphosate leads to endocrine disruption. Food Chem Toxicol. 2017 Feb;100:247-252. PMID: 28017703

Mesnage R, Phedonos A, Biserni M, Arno M, Balu S, Corton JC, Ugarte R, Antoniou MN. Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents. Food Chem Toxicol. 2017 Oct;108(Pt A):30-42. PMID: 28711546

Defarge N, Takács E, Lozano VL, Mesnage R, Spiroux de Vendômois J, Séralini GE, Székács A. Co-Formulants in Glyphosate-Based Herbicides Disrupt Aromatase Activity in Human Cells below Toxic Levels. Int J Environ Res Public Health. 2016 Feb 26;13(3). PMID: 26927151

Pandey A, Rudraiah M. Analysis of endocrine disruption effect of Roundup_® in adrenal gland of male rats. Toxicol Rep. 2015 Aug 3;2:1075-1085. PMID: 28962449

Gasnier C, Dumont C, Benachour N, Clair E, Chagnon MC, Séralini GE. Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines. Toxicology. 2009 Aug 21;262(3):184-91. PMID: 19539684

 

Digestion

Chłopecka M, Mendel M, Dziekan N, Karlik W. The effect of glyphosate-based herbicide Roundup and its co-formulant, POEA, on the motoric activity of rat intestine – In vitro study. Environ Toxicol Pharmacol. 2017 Jan;49:156-162. PMID: 28049099

Jyoti W, Thabah MM, Rajagopalan S, Hamide A. Esophageal perforation and death following glyphosate poisoning. J Postgrad Med. 2014 Jul-Sep;60(3):346-7. PMID: 25121387

Chłopecka M, Mendel M, Dziekan N, Karlik W. Glyphosate affects the spontaneous motoric activity of intestine at very low doses – in vitro study. Pestic Biochem Physiol. 2014 Jul;113:25-30. PMID: 25052523

Samsel A, Seneff S. Glyphosate, pathways to modern diseases II: Celiac sprue and gluten intolerance. Interdiscip Toxicol. 2013 Dec;6(4):159-84. PMID: 24678255

Chen HH, Lin JL, Huang WH, Weng CH, Lee SY, Hsu CW, Chen KH, Wang IK, Liang CC, Chang CT, Yen TH. Spectrum of corrosive esophageal injury after intentional paraquat or glyphosate-surfactant herbicide ingestion. Int J Gen Med. 2013 Aug 14;6:677-83. PMID: 23983484

Larsen K, Najle R, Lifschitz A, Virkel G. Effects of sub-lethal exposure of rats to the herbicide glyphosate in drinking water: glutathione transferase enzyme activities, levels of reduced glutathione and lipid peroxidation in liver, kidneys and small intestine. Environ Toxicol Pharmacol. 2012 Nov;34(3):811-8. PMID: 23044091

Frappart M, Vouriot D, Lemoine L, Floch T, Leon A. A fatal acute poisoning with glyphosate: importance of gastrointestinal toxicity. Ann Fr Anesth Reanim. 2011 Nov;30(11):852-4. PMID: 21981851

Palli E, Makris D, Diakaki C, Garoufalis G, Zakynthinos E. Rapture of the large intestine caused by severe oral glyphosate-surfactant intoxication. Am J Emerg Med. 2011 May;29(4):459-60. PMID: 21296522

Vasiluk L, Pinto LJ, Moore MM. Oral bioavailability of glyphosate: studies using two intestinal cell lines. Environ Toxicol Chem. 2005 Jan;24(1):153-60. PMID: 15683179

 

Parkinson’s Disease

Goldstein DA, Dunn SE, Karberg K. “Reversible Parkinsonism” following glyphosate exposure. Parkinsonism Relat Disord. 2018 Jun 6. pii: S1353-8020(18)30271-2. PMID: 29903583

Zheng Q, Yin J, Zhu L, Jiao L, Xu Z. Reversible Parkinsonism induced by acute exposure glyphosate. Parkinsonism Relat Disord. 2018 May;50:121. PMID: 29398490

Wang G, Fan XN, Tan YY, Cheng Q, Chen SD. Parkinsonism after chronic occupational exposure to glyphosate. Parkinsonism Relat Disord. 2011 Jul;17(6):486-7. PMID: 21367645

 

Fish, Amphibians & Reptiles

Burella PM, Odetti LM, Simoniello MF, Poletta GL. Oxidative damage and antioxidant defense in Caiman latirostris (Broad-snouted caiman) exposed in ovo to pesticide formulations. Ecotoxicol Environ Saf. 2018 Jun 13;161:437-443. PMID: 29908455

Bókony V, Üveges B, Ujhegyi N, Verebélyi V, Nemesházi E, Csíkvári O, Hettyey A. Endocrine disruptors in breeding ponds and reproductive health of toads in agricultural, urban and natural landscapes. Sci Total Environ. 2018 Sep 1;634:1335-1345. PMID: 29710633

Lugowska K. The effects of Roundup on gametes and early development of common carp (Cyprinus carpio L). Fish Physiol Biochem. 2018 Apr 7. PMID: 29627927

Gonçalves BB, Nascimento NF, Santos MP, Bertolini RM, Yasui GS, Giaquinto PC. Low concentrations of glyphosate-based herbicide cause complete loss of sperm motility of yellowtail tetra fish Astyanax lacustris. J Fish Biol. 2018 Apr;92(4):1218-1224. PMID: 29488225

Kittle RP, McDermid KJ, Muehlstein L, Balazs GH. Effects of glyphosate herbicide on the gastrointestinal microflora of Hawaiian green turtles (Chelonia mydas) Linnaeus. Mar Pollut Bull. 2018 Feb;127:170-174. PMID: 29475651

Jin J, Kurobe T, Ramírez-Duarte WF, Bolotaolo MB, Lam CH, Pandey PK, Hung TC, Stillway ME, Zweig L, Caudill J, Lin L, Teh SJ. Sub-lethal effects of herbicides penoxsulam, imazamox, fluridone and glyphosate on Delta Smelt (Hypomesus transpacificus). Aquat Toxicol. 2018 Apr;197:79-88. PMID: 29448126

Persch TSP, da Silva PR, Dos Santos SHD, de Freitas BS, Oliveira GT. Changes in intermediate metabolism and oxidative balance parameters in sexually matured three-barbeled catfishes exposed to herbicides from rice crops (Roundup_®, Primoleo_® and Facet_®). Environ Toxicol Pharmacol. 2018 Mar;58:170-179. PMID: 29408759

Reno U, Doyle SR, Momo FR, Regaldo L, Gagneten AM. Effects of glyphosate formulations on the population dynamics of two freshwater cladoceran species. Ecotoxicology. 2018 Feb 5. PMID: 29404864

Fiorino E, Sehonova P, Plhalova L, Blahova J, Svobodova Z, Faggio C. Effects of glyphosate on early life stages: comparison between Cyprinus carpio and Danio rerio. Environ Sci Pollut Res Int. 2018 Mar;25(9):8542-8549. PMID: 29313199

Zebral YD, Lansini LR, Costa PG, Roza M, Bianchini A, Robaldo RB. A glyphosate-based herbicide reduces fertility, embryonic upper thermal tolerance and alters embryonic diapause of the threatened annual fish Austrolebias nigrofasciatus. Chemosphere. 2018 Apr;196:260-269. PMID: 29306198

Bridi D, Altenhofen S, Gonzalez JB, Reolon GK, Bonan CD. Glyphosate and Roundup_® alter morphology and behavior in zebrafish. Toxicology. 2017 Dec 1;392:32-39. PMID: 29032223

de Moura FR, da Silva Lima RR, da Cunha APS, da Costa Marisco P, Aguiar DH, Sugui MM, Sinhorin AP, Sinhorin VDG. Effects of glyphosate-based herbicide on pintado da Amazônia: Hematology, histological aspects, metabolic parameters and genotoxic potential. Environ Toxicol Pharmacol. 2017 Dec;56:241-248. PMID: 29031220

Hong Y, Yang X, Yan G, Huang Y, Zuo F, Shen Y, Ding Y, Cheng Y. Effects of glyphosate on immune responses and haemocyte DNA damage of Chinese mitten crab, Eriocheir sinensis. Fish Shellfish Immunol. 2017 Dec;71:19-27. PMID: 28962885

Héritier L, Duval D, Galinier R, Meistertzheim AL, Verneau O. Oxidative stress induced by glyphosate-based herbicide on freshwater turtles. Environ Toxicol Chem. 2017 Dec;36(12):3343-3350. PMID: 28833383

de Moura FR, Brentegani KR, Gemelli A, Sinhorin AP, Sinhorin VDG. Oxidative stress in the hybrid fish jundiara (Leiarius marmoratus × Pseudoplatystoma reticulatum) exposed to Roundup Original_®. Chemosphere. 2017 Oct;185:445-451. PMID: 28711796

Bókony V, Mikó Z, Móricz ÁM, Krüzselyi D, Hettyey A. Chronic exposure to a glyphosate-based herbicide makes toad larvae more toxic. Proc Biol Sci. 2017 Jul 12;284(1858). PMID: 28679726

Mikó Z, Ujszegi J, Gál Z, Hettyey A. Standardize or Diversify Experimental Conditions in Ecotoxicology? A Case Study on Herbicide Toxicity to Larvae of Two Anuran Amphibians. Arch Environ Contam Toxicol. 2017 Nov;73(4):562-569. PMID: 28660298

Héritier L, Meistertzheim AL, Verneau O. Oxidative stress biomarkers in the Mediterranean pond turtle (Mauremys leprosa) reveal contrasted aquatic environments in Southern France. Chemosphere. 2017 Sep;183:332-338. PMID: 28554017

Li MH, Ruan LY, Zhou JW, Fu YH, Jiang L, Zhao H, Wang JS. Metabolic profiling of goldfish (Carassius auratis) after long-term glyphosate-based herbicide exposure. Aquat Toxicol. 2017 Jul;188:159-169. PMID: 28528318

Zhang S, Xu J, Kuang X, Li S, Li X, Chen D, Zhao X, Feng X. Biological impacts of glyphosate on morphology, embryo biomechanics and larval behavior in zebrafish (Danio rerio). Chemosphere. 2017 Aug;181:270-280. PMID: 28448908

Antunes AM, Rocha TL, Pires FS, de Freitas MA, Leite VRMC, Arana S, Moreira PC, Sabóia-Morais SMT. Gender-specific histopathological response in guppies Poecilia reticulata exposed to glyphosate or its metabolite aminomethylphosphonic acid. J Appl Toxicol. 2017 Sep;37(9):1098-1107. PMID: 28425566

Qin Y, Li X, Xiang Y, Wu D, Bai L, Li Z, Liang Y. Toxic effects of glyphosate on diploid and triploid fin cell lines from Misgurnus anguillicaudatus. Chemosphere. 2017 Aug;180:356-364. PMID: 28415036

Druart C, Gimbert F, Scheifler R, de Vaufleury A. A full life-cycle bioassay with Cantareus aspersus shows reproductive effects of a glyphosate-based herbicide suggesting potential endocrine disruption. Environ Pollut. 2017 Jul;226:240-249. PMID: 28395863

Sulukan E, Köktürk M, Ceylan H, Beydemir Ş, Işik M, Atamanalp M, Ceyhun SB. An approach to clarify the effect mechanism of glyphosate on body malformations during embryonic development of zebrafish (Daino rerio). Chemosphere. 2017 Aug;180:77-85. PMID: 28391155

Romansic JM, Johnson JE, Wagner RS, Hill RH, Gaulke CA, Vredenburg VT, Blaustein AR. Complex interactive effects of water mold, herbicide, and the fungus Batrachochytrium dendrobatidis on Pacific treefrog Hyliola regilla hosts. Dis Aquat Organ. 2017 Mar 21;123(3):227-238. PMID: 28322209

Sánchez JA, Varela AS Junior, Corcini CD, da Silva JC, Primel EG, Caldas S, Klein RD, Martins CM. Effects of Roundup formulations on biochemical biomarkers and male sperm quality of the live bearing Jenynsia multidentata. Chemosphere. 2017 Jun;177:200-210. PMID: 28288428

Mikó Z, Ujszegi J, Gál Z, Hettyey A. Effects of a glyphosate-based herbicide and predation threat on the behaviour of agile frog tadpoles. Ecotoxicol Environ Saf. 2017 Jun;140:96-102. PMID: 28242374

Séguin A, Mottier A, Perron C, Lebel JM, Serpentini A, Costil K. Sub-lethal effects of a glyphosate-based commercial formulation and adjuvants on juvenile oysters (Crassostrea gigas) exposed for 35days. Mar Pollut Bull. 2017 Apr 15;117(1-2):348-358. PMID: 28202277

Giaquinto PC, de Sá MB, Sugihara VS, Gonçalves BB, Delício HC, Barki A. Effects of Glyphosate-Based Herbicide Sub-Lethal Concentrations on Fish Feeding Behavior. Bull Environ Contam Toxicol. 2017 Apr;98(4):460-464. PMID: 28188320

Lopes FM, Caldas SS, Primel EG, da Rosa CE. Glyphosate Adversely Affects Danio rerio Males: Acetylcholinesterase Modulation and Oxidative Stress. Zebrafish. 2017 Apr;14(2):97-105. PMID: 27906609

de Melo Tarouco F, de Godoi FGA, Velasques RR, da Silveira Guerreiro A, Geihs MA, da Rosa CE. Effects of the herbicide Roundup on the polychaeta Laeonereis acuta: Cholinesterases and oxidative stress. Ecotoxicol Environ Saf. 2017 Jan;135:259-266. PMID: 27750093

Lasier PJ, Urich ML, Hassan SM, Jacobs WN, Bringolf RB, Owens KM. Changing agricultural practices: potential consequences to aquatic organisms. Environ Monit Assess. 2016 Dec;188(12):672. PMID: 27848110

Dos Santos APR, Rocha TL, Borges CL, Bailão AM, de Almeida Soares CM, de Sabóia-Morais SMT. A glyphosate-based herbicide induces histomorphological and protein expression changes in the liver of the female guppy Poecilia reticulata. Chemosphere. 2017 Feb;168:933-943. PMID: 27836263

de Saraiva AS, Sarmento RA, Pedro-Neto M, Teodoro AV, Erasmo EA, Belchior DC, de Azevedo EB. Glyphosate sub-lethal toxicity to non-target organisms occurring in Jatropha curcas plantations in Brazil. Exp Appl Acarol. 2016 Oct;70(2):179-87. PMID: 27502112

Baier F, Gruber E, Hein T, Bondar-Kunze E, Ivanković M, Mentler A, Brühl CA, Spangl B, Zaller JG. Non-target effects of a glyphosate-based herbicide on Common toad larvae (Bufo bufo, Amphibia) and associated algae are altered by temperature. PeerJ. 2016 Nov 1;4:e2641. PMID: 27833808

Burraco P, Gomez-Mestre I. Physiological Stress Responses in Amphibian Larvae to Multiple Stressors Reveal Marked Anthropogenic Effects even below Lethal Levels. Physiol Biochem Zool. 2016 Nov/Dec;89(6):462-472. PMID: 27792531

Wagner N, Müller H, Viertel B. Effects of a commonly used glyphosate-based herbicide formulation on early developmental stages of two anuran species. Environ Sci Pollut Res Int. 2017 Jan;24(2):1495-1508. PMID: 27785717

Burella PM, Simoniello MF, Poletta GL. Evaluation of Stage-Dependent Genotoxic Effect of Roundup_® (Glyphosate) on Caiman latirostris Embryos. Arch Environ Contam Toxicol. 2017 Jan;72(1):50-57. PMID: 27771755

Bach NC, Natale GS, Somoza GM, Ronco AE. Effect on the growth and development and induction of abnormalities by a glyphosate commercial formulation and its active ingredient during two developmental stages of the South-American Creole frog, Leptodactylus latrans. Environ Sci Pollut Res Int. 2016 Dec;23(23):23959-23971. PMID: 27638798

Hansen LR, Roslev P. Behavioral responses of juvenile Daphnia magna after exposure to glyphosate and glyphosate-copper complexes. Aquat Toxicol. 2016 Oct;179:36-43. PMID: 27564378

Roy NM, Ochs J, Zambrzycka E, Anderson A. Glyphosate induces cardiovascular toxicity in Danio rerio. Environ Toxicol Pharmacol. 2016 Sep;46:292-300. PMID: 27525560

da Rosa JG, de Abreu MS, Giacomini AC, Koakoski G, Kalichak F, Oliveira TA, de Alcântara Barcellos HH, Barreto RE, Barcellos LJ. Fish Aversion and Attraction to Selected Agrichemicals. Arch Environ Contam Toxicol. 2016 Oct;71(3):415-22. PMID: 27423874

Monte TC, Garcia J, Gentile R, de Vasconcellos MC, Souza J, Braga BV, Maldonado A Jr. In vivo and in vitro effects of the herbicide Roundup on developmental stages of the trematode Echinostoma paraensei. Exp Parasitol. 2016 Oct;169:43-50. PMID: 27373431

Velasques RR, Sandrini JZ, da Rosa CE. Roundup in Zebrafish: Effects on Oxidative Status and Gene Expression. Zebrafish. 2016 Oct;13(5):432-41. PMID: 27315435

Wagner N, Veith M, Lötters S, Viertel B. Population and life-stage-specific effects of two herbicide formulations on the aquatic development of European common frogs (Rana temporaria). Environ Toxicol Chem. 2017 Jan;36(1):190-200. PMID: 27291460

Soloneski S, Ruiz de Arcaute C, Larramendy ML. Genotoxic effect of a binary mixture of dicamba- and glyphosate-based commercial herbicide formulations on Rhinella arenarum (Hensel, 1867) (Anura, Bufonidae) late-stage larvae. Environ Sci Pollut Res Int. 2016 Sep;23(17):17811-21. PMID: 27250090

Rissoli RZ, Abdalla FC, Costa MJ, Rantin FT, McKenzie DJ, Kalinin AL. Effects of glyphosate and the glyphosate based herbicides Roundup Original and Roundup Transorb on respiratory morphophysiology of bullfrog tadpoles. Chemosphere. 2016 Aug;156:37-44. PMID: 27160633

Schaumburg LG, Siroski PA, Poletta GL, Mudry MD. Genotoxicity induced by Roundup (Glyphosate) in tegu lizard (Salvator merianae) embryos. Pestic Biochem Physiol. 2016 Jun;130:71-78. PMID: 27155487

Sani A, Idris MK. Acute toxicity of herbicide (glyphosate) in Clarias gariepinus juveniles. Toxicol Rep. 2016 May 6;3:513-515. PMID: 28959574

Brodeur JC, Malpel S, Anglesio AB, Cristos D, D’Andrea MF, Poliserpi MB. Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus). Chemosphere. 2016 Jul;155:429-435. PMID: 27139121

Louch J, Tatum V, Allen G, Hale VC, McDonnell J, Danehy RJ, Ice G. Potential risks to freshwater aquatic organisms following a silvicultural application of herbicides in Oregon’s Coast Range. Integr Environ Assess Manag. 2017 Mar;13(2):396-409. PMID: 27064429

Geyer RL, Smith GR, Rettig JE. Effects of Roundup formulations, nutrient addition, and Western mosquitofish (Gambusia affinis) on aquatic communities. Environ Sci Pollut Res Int. 2016 Jun;23(12):11729-39. PMID: 26944427

Gandhi JS, Cecala KK. Interactive effects of temperature and glyphosate on the behavior of blue ridge two-lined salamanders (Eurycea wilderae). Environ Toxicol Chem. 2016 Sep;35(9):2297-303. PMID: 26872413

Pérez-Iglesias JM, Franco-Belussi L, Moreno L, Tripole S, de Oliveira C, Natale GS. Effects of glyphosate on hepatic tissue evaluating melanomacrophages and erythrocytes responses in neotropical anuran Leptodactylus latinasus. Environ Sci Pollut Res Int. 2016 May;23(10):9852-61. PMID: 26856864

Carpenter JK, Monks JM, Nelson N. The effect of two glyphosate formulations on a small, diurnal lizard (Oligosoma polychroma). Ecotoxicology. 2016 Apr;25(3):548-54. PMID: 26841966

Roy NM, Carneiro B, Ochs J. Glyphosate induces neurotoxicity in zebrafish. Environ Toxicol Pharmacol. 2016 Mar;42:45-54. PMID: 26773362

Siroski PA, Poletta GL, Latorre MA, Merchant ME, Ortega HH, Mudry MD. Immunotoxicity of commercial-mixed glyphosate in broad snouted caiman (Caiman latirostris). Chem Biol Interact. 2016 Jan 25;244:64-70. PMID: 26658029

Henao Muñoz LM, Montes Rojas CM, Bernal Bautista MH. Acute toxicity and sublethal effects of the mixture glyphosate (Roundup Active) and Cosmo-Flux 411F to anuran embryos and tadpoles of four Colombian species. Rev Biol Trop. 2015 Mar;63(1):223-33. PMID: 26299127

Rocha TL, Santos AP, Yamada ÁT, Soares CM, Borges CL, Bailão AM, Sabóia-Morais SM. Proteomic and histopathological response in the gills of Poecilia reticulata exposed to glyphosate-based herbicide. Environ Toxicol Pharmacol. 2015 Jul;40(1):175-86. PMID: 26141659

Vincent K, Davidson C. The toxicity of glyphosate alone and glyphosate-surfactant mixtures to western toad (Anaxyrus boreas) tadpoles. Environ Toxicol Chem. 2015 Dec;34(12):2791-5. PMID: 26084619

Goulart TL, Boyle RT, Souza MM. Cytotoxicity of the association of pesticides Roundup Transorb and Furadan 350 SC on the zebrafish cell line, ZF-L. Toxicol In Vitro. 2015 Oct;29(7):1377-84. PMID: 26065625

Braz-Mota S, Sadauskas-Henrique H, Duarte RM, Val AL, Almeida-Val VM. Roundup exposure promotes gills and liver impairments, DNA damage and inhibition of brain cholinergic activity in the Amazon teleost fish Colossoma macropomum. Chemosphere. 2015 Sep;135:53-60. PMID: 25898390

Ma J, Li X. Alteration in the cytokine levels and histopathological damage in common carp induced by glyphosate. Chemosphere. 2015 Jun;128:293-8. PMID: 25747155

Baurand PE, Capelli N, de Vaufleury A. Genotoxicity assessment of pesticides on terrestrial snail embryos by analysis of random amplified polymorphic DNA profiles. J Hazard Mater. 2015 Nov 15;298:320-7. PMID: 26160746

Douros DL, Gaines KF, Novak JM. Atrazine and glyphosate dynamics in a lotic ecosystem: the common snapping turtle as a sentinel species. Environ Monit Assess. 2015 Mar;187(3):114. PMID: 25678354

Wood L, Welch AM. Assessment of interactive effects of elevated salinity and three pesticides on life history and behavior of southern toad (Anaxyrus terrestris) tadpoles. Environ Toxicol Chem. 2015 Mar;34(3):667-76. PMID: 25523942

Mottier A, Séguin A, Devos A, Pabic CL, Voiseux C, Lebel JM, Serpentini A, Fievet B, Costil K. Effects of subchronic exposure to glyphosate in juvenile oysters (Crassostrea gigas): From molecular to individual levels. Mar Pollut Bull. 2015 Jun 30;95(2):665-77. PMID: 25455786

Moore H, Chivers DP, Ferrari MC. Sub-lethal effects of Roundup™ on tadpole anti-predator responses. Ecotoxicol Environ Saf. 2015 Jan;111:281-5. PMID: 25450945

Ma J, Bu Y, Li X. Immunological and histopathological responses of the kidney of common carp (Cyprinus carpio L.) sublethally exposed to glyphosate. Environ Toxicol Pharmacol. 2015 Jan;39(1):1-8. PMID: 25434756

Edge C, Thompson D, Hao C, Houlahan J. The response of amphibian larvae to exposure to a glyphosate-based herbicide (Roundup WeatherMax) and nutrient enrichment in an ecosystem experiment. Ecotoxicol Environ Saf. 2014 Nov;109:124-32. PMID: 25173748

Kreutz LC, Pavan TR, Alves AG, Correia AG, Barriquel B, Santos ED, Barcellos LJ. Increased immunoglobulin production in silver catfish (Rhamdia quelen) exposed to agrichemicals. Braz J Med Biol Res. 2014 Jun;47(6):499-504. PMID: 25009838

Marques A, Guilherme S, Gaivão I, Santos MA, Pacheco M. Progression of DNA damage induced by a glyphosate-based herbicide in fish (Anguilla anguilla) upon exposure and post-exposure periods–insights into the mechanisms of genotoxicity and DNA repair. Comp Biochem Physiol C Toxicol Pharmacol. 2014 Nov;166:126-33. PMID: 25110831

Lopes FM, Varela Junior AS, Corcini CD, da Silva AC, Guazzelli VG, Tavares G, da Rosa CE. Effect of glyphosate on the sperm quality of zebrafish Danio rerio. Aquat Toxicol. 2014 Oct;155:322-6. PMID: 25089920

Guilherme S, Santos MA, Gaivão I, Pacheco M. Are DNA-damaging effects induced by herbicide formulations (Roundup and Garlon) in fish transient and reversible upon cessation of exposure? Aquat Toxicol. 2014 Oct;155:213-21. PMID: 25058560

Koakoski G, Quevedo RM, Ferreira D, Oliveira TA, da Rosa JG, de Abreu MS, Gusso D, Marqueze A, Kreutz LC, Giacomini AC, Fagundes M, Barcellos LJ. Agrichemicals chronically inhibit the cortisol response to stress in fish. Chemosphere. 2014 Oct;112:85-91. PMID: 25048892

Lanctôt C, Navarro-Martín L, Robertson C, Park B, Jackman P, Pauli BD, Trudeau VL. Effects of glyphosate-based herbicides on survival, development, growth and sex ratios of wood frog (Lithobates sylvaticus) tadpoles. II: agriculturally relevant exposures to Roundup WeatherMax and Vision under laboratory conditions. Aquat Toxicol. 2014 Sep;154:291-303. PMID: 24912403

Baker LF, Mudge JF, Houlahan JE, Thompson DG, Kidd KA. The direct and indirect effects of a glyphosate-based herbicide and nutrients on Chironomidae (Diptera) emerging from small wetlands. Environ Toxicol Chem. 2014 Sep;33(9):2076-85. PMID: 24899169

Navarro-Martín L, Lanctôt C, Jackman P, Park BJ, Doe K, Pauli BD, Trudeau VL. Effects of glyphosate-based herbicides on survival, development, growth and sex ratios of wood frogs (Lithobates sylvaticus) tadpoles. I: chronic laboratory exposures to VisionMax. Aquat Toxicol. 2014 Sep;154:278-90. PMID: 24878356

Sinhorin VD, Sinhorin AP, Teixeira JM, Miléski KM, Hansen PC, Moreira PS, Kawashita NH, Baviera AM, Loro VL. Effects of the acute exposition to glyphosate-based herbicide on oxidative stress parameters and antioxidant responses in a hybrid Amazon fish surubim (Pseudoplatystoma sp). Ecotoxicol Environ Saf. 2014 Aug;106:181-7. PMID: 24840881

Avigliano L, Alvarez N, Loughlin CM, Rodríguez EM. Effects of glyphosate on egg incubation, larvae hatching, and ovarian rematuration in the estuarine crab Neohelice granulata. Environ Toxicol Chem. 2014 Aug;33(8):1879-84. PMID: 24831879

Yusof S, Ismail A, Alias MS. Effect of glyphosate-based herbicide on early life stages of Java medaka (Oryzias javanicus): a potential tropical test fish. Mar Pollut Bull. 2014 Aug 30;85(2):494-8. PMID: 24731878

Guilherme S, Santos MA, Gaivão I, Pacheco M. DNA and chromosomal damage induced in fish (Anguilla anguilla L.) by aminomethylphosphonic acid (AMPA)–the major environmental breakdown product of glyphosate. Environ Sci Pollut Res Int. 2014;21(14):8730-9. PMID: 24696215

Armiliato N, Ammar D, Nezzi L, Straliotto M, Muller YM, Nazari EM. Changes in ultrastructure and expression of steroidogenic factor-1 in ovaries of zebrafish Danio rerio exposed to glyphosate. J Toxicol Environ Health A. 2014;77(7):405-14. PMID: 24617544

Avigliano L, Fassiano AV, Medesani DA, Ríos de Molina MC, Rodríguez EM. Effects of glyphosate on growth rate, metabolic rate and energy reserves of early juvenile crayfish, Cherax quadricarinatus M. Bull Environ Contam Toxicol. 2014 Jun;92(6):631-5. PMID: 24584268

Moreno NC, Sofia SH, Martinez CB. Genotoxic effects of the herbicide Roundup Transorb and its active ingredient glyphosate on the fish Prochilodus lineatus. Environ Toxicol Pharmacol. 2014 Jan;37(1):448-54. PMID: 24448465

dos Santos KC, Martinez CB. Genotoxic and biochemical effects of atrazine and Roundup, alone and in combination, on the Asian clam Corbicula fluminea. Ecotoxicol Environ Saf. 2014 Feb;100:7-14. PMID: 24433785

Uren Webster TM, Laing LV, Florance H, Santos EM. Effects of glyphosate and its formulation, roundup, on reproduction in zebrafish (Danio rerio). Environ Sci Technol. 2014 Jan 21;48(2):1271-9. PMID: 24364672

Hanlon SM, Parris MJ. The interactive effects of chytrid fungus, pesticides, and exposure timing on gray treefrog (Hyla versicolor) larvae. Environ Toxicol Chem. 2014 Jan;33(1):216-22. PMID: 24259231

Omran NE, Salama WM. The endocrine disruptor effect of the herbicides atrazine and glyphosate on Biomphalaria alexandrina snails. Toxicol Ind Health. 2016 Apr;32(4):656-65. PMID: 24215068

Gholami-Seyedkolaei SJ, Mirvaghefi A, Farahmand H, Kosari AA. Effect of a glyphosate-based herbicide in Cyprinus carpio: assessment of acetylcholinesterase activity, hematological responses and serum biochemical parameters. Ecotoxicol Environ Saf. 2013 Dec;98:135-41. PMID: 24075644

Mateos-Naranjo E, Perez-Martin A. Effects of sub-lethal glyphosate concentrations on growth and photosynthetic performance of non-target species Bolboschoenus maritimus. Chemosphere. 2013 Nov;93(10):2631-8. PMID: 24161579

De Souza Filho J, Sousa CC, Da Silva CC, De Sabóia-Morais SM, Grisolia CK. Mutagenicity and genotoxicity in gill erythrocyte cells of Poecilia reticulata exposed to a glyphosate formulation. Bull Environ Contam Toxicol. 2013 Nov;91(5):583-7. PMID: 24042842

Harayashiki CA, Varela AS Jr, Machado AA, Cabrera Lda C, Primel EG, Bianchini A, Corcini CD. Toxic effects of the herbicide Roundup in the guppy Poecilia vivipara acclimated to fresh water. Aquat Toxicol. 2013 Oct 15;142-143:176-84. PMID: 24036434

Güngördü A. Comparative toxicity of methidathion and glyphosate on early life stages of three amphibian species: Pelophylax ridibundus, Pseudepidalea viridis, and Xenopus laevis. Aquat Toxicol. 2013 Sep 15;140-141:220-8. PMID: 23831689

Nwani CD, Nagpure NS, Kumar R, Kushwaha B, Lakra WS. DNA damage and oxidative stress modulatory effects of glyphosate-based herbicide in freshwater fish, Channa punctatus. Environ Toxicol Pharmacol. 2013 Sep;36(2):539-47. PMID: 23816461

Wagner N, Reichenbecher W, Teichmann H, Tappeser B, Lötters S. Questions concerning the potential impact of glyphosate-based herbicides on amphibians. Environ Toxicol Chem. 2013 Aug;32(8):1688-700. PMID: 23637092

Meza-Joya FL, Ramírez-Pinilla MP, Fuentes-Lorenzo JL. Toxic, cytotoxic, and genotoxic effects of a glyphosate formulation (RoundupSL-Cosmoflux 411F) in the direct-developing frog Eleutherodactylus johnstonei. Environ Mol Mutagen. 2013 Jun;54(5):362-73. PMID: 23625742

Yadav SS, Giri S, Singha U, Boro F, Giri A. Toxic and genotoxic effects of Roundup on tadpoles of the Indian skittering frog (Euflictis cyanophlyctis) in the presence and absence of predator stress. Aquat Toxicol. 2013 May 15;132-133:1-8. PMID: 23454306

Sandrini JZ, Rola RC, Lopes FM, Buffon HF, Freitas MM, Martins Cde M, da Rosa CE. Effects of glyphosate on cholinesterase activity of the mussel Perna perna and the fish Danio rerio and Jenynsia multidentata: in vitro studies. Aquat Toxicol. 2013 Apr 15;130-131:171-3. PMID: 23411353

Mottier A, Kientz-Bouchart V, Serpentini A, Lebel JM, Jha AN, Costil K. Effects of glyphosate-based herbicides on embryo-larval development and metamorphosis in the Pacific oyster, Crassostrea gigas. Aquat Toxicol. 2013 Mar 15;128-129:67-78. PMID: 23277103

Vera-Candioti J, Soloneski S, Larramendy ML. Evaluation of the genotoxic and cytotoxic effects of glyphosate-based herbicides in the ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842). Ecotoxicol Environ Saf. 2013 Mar;89:166-73. PMID: 23273868

Latorre MA, López González EC, Larriera A, Poletta GL, Siroski PA. Effects of in vivo exposure to Roundup on immune system of Caiman latirostris. J Immunotoxicol. 2013 Oct-Dec;10(4):349-54. PMID: 23244546

de Castilhos Ghisi N, Cestari MM. Genotoxic effects of the herbicide Roundup in the fish Corydoras paleatus (Jenyns 1842) after short-term, environmentally low concentration exposure. Environ Monit Assess. 2013 Apr;185(4):3201-7. PMID: 22821326

Shiogiri NS, Paulino MG, Carraschi SP, Baraldi FG, da Cruz C, Fernandes MN. Acute exposure of a glyphosate-based herbicide affects the gills and liver of the Neotropical fish, Piaractus mesopotamicus. Environ Toxicol Pharmacol. 2012 Sep;34(2):388-396. PMID: 22743578

Relyea RA. New effects of Roundup on amphibians: predators reduce herbicide mortality; herbicides induce antipredator morphology. Ecol Appl. 2012 Mar;22(2):634-47. PMID: 22611860

Vera MS, Di Fiori E, Lagomarsino L, Sinistro R, Escaray R, Iummato MM, Juárez A, Ríos de Molina Mdel C, Tell G, Pizarro H. Direct and indirect effects of the glyphosate formulation Glifosato Atanor on freshwater microbial communities. Ecotoxicology. 2012 Oct;21(7):1805-16. PMID: 22539117

Guilherme S, Santos MA, Barroso C, Gaivão I, Pacheco M. Differential genotoxicity of Roundup formulation and its constituents in blood cells of fish (Anguilla anguilla): considerations on chemical interactions and DNA damaging mechanisms. Ecotoxicology. 2012 Jul;21(5):1381-90. PMID: 22526921

Paetow LJ, Daniel McLaughlin J, Cue RI, Pauli BD, Marcogliese DJ. Effects of herbicides and the chytrid fungus Batrachochytrium dendrobatidis on the health of post-metamorphic northern leopard frogs (Lithobates pipiens). Ecotoxicol Environ Saf. 2012 Jun;80:372-80. PMID: 22520452

Mensah PK, Palmer CG, Muller WJ. Lipid peroxidation in the freshwater shrimp Caridina nilotica as a biomarker of Roundup herbicide pollution of freshwater systems in South Africa. Water Sci Technol. 2012;65(9):1660-6. PMID: 22508130

Siddiqui S, Meghvansi MK, Khan SS. Glyphosate, alachor and maleic hydrazide have genotoxic effect on Trigonella foenum-graecum L. Bull Environ Contam Toxicol. 2012 May;88(5):659-65. PMID: 22392005

Guilherme S, Gaivão I, Santos MA, Pacheco M. DNA damage in fish (Anguilla anguilla) exposed to a glyphosate-based herbicide — elucidation of organ-specificity and the role of oxidative stress. Mutat Res. 2012 Mar 18;743(1-2):1-9. PMID: 22266476

Boonsoong B, Bullangpoti V. Acute toxicity of Roundup and carbosulfan to the Thai fairy shrimp, Branchinella thailandensis. Commun Agric Appl Biol Sci. 2012;77(4):431-7. PMID: 23885411

Moore LJ, Fuentes L, Rodgers JH Jr, Bowerman WW, Yarrow GK, Chao WY, Bridges WC Jr. Relative toxicity of the components of the original formulation of Roundup to five North American anurans. Ecotoxicol Environ Saf. 2012 Apr;78:128-33. PMID: 22137360

Akcha F, Spagnol C, Rouxel J. Genotoxicity of diuron and glyphosate in oyster spermatozoa and embryos. Aquat Toxicol. 2012 Jan 15;106-107:104-13. PMID: 22115909

Gahl MK, Pauli BD, Houlahan JE. Effects of chytrid fungus and a glyphosate-based herbicide on survival and growth of wood frogs (Lithobates sylvaticus). Ecol Appl. 2011 Oct;21(7):2521-9. PMID: 22073641

Geret F, Burgeot T, Haure J, Gagnaire B, Renault T, Communal PY, Samain JF. Effects of low-dose exposure to pesticide mixture on physiological responses of the Pacific oyster, Crassostrea gigas. Environ Toxicol. 2013 Dec;28(12):689-99. PMID: 22012874

Hued AC, Oberhofer S, de los Ángeles Bistoni M. Exposure to a commercial glyphosate formulation (Roundup) alters normal gill and liver histology and affects male sexual activity of Jenynsia multidentata (Anablepidae, Cyprinodontiformes). Arch Environ Contam Toxicol. 2012 Jan;62(1):107-17. PMID: 21643816

Edge CB, Gahl MK, Pauli BD, Thompson DG, Houlahan JE. Exposure of juvenile green frogs (Lithobates clamitans) in littoral enclosures to a glyphosate-based herbicide. Ecotoxicol Environ Saf. 2011 Jul;74(5):1363-9. PMID: 21536331

Ruamthum W, Visetson S, Milne JR, Bullangpoti V. Effect of glyphosate-based herbicide on acetylcholinesterase activity in tadpoles, Hoplobatrachus rugulosus. Commun Agric Appl Biol Sci. 2011;76(4):923-30. PMID: 22702209

Jones DK, Hammond JI, Relyea RA. Competitive stress can make the herbicide Roundup more deadly to larval amphibians. Environ Toxicol Chem. 2011 Feb;30(2):446-54. PMID: 21038363

Kreutz LC, Gil Barcellos LJ, de Faria Valle S, de Oliveira Silva T, Anziliero D, Davi dos Santos E, Pivato M, Zanatta R. Altered hematological and immunological parameters in silver catfish (Rhamdia quelen) following short term exposure to sublethal concentration of glyphosate. Fish Shellfish Immunol. 2011 Jan;30(1):51-7. PMID: 20883798

Slaninova A, Smutna M, Modra H, Svobodova Z. A review: oxidative stress in fish induced by pesticides. Neuro Endocrinol Lett. 2009;30 Suppl 1:2-12. PMID: 20027135

Modesto KA, Martinez CB. Roundup causes oxidative stress in liver and inhibits acetylcholinesterase in muscle and brain of the fish Prochilodus lineatus. Chemosphere. 2010 Jan;78(3):294-9. PMID: 19910015

Bernal MH, Solomon KR, Carrasquilla G. Toxicity of formulated glyphosate (glyphos) and cosmo-flux to larval and juvenile colombian frogs 2. Field and laboratory microcosm acute toxicity. J Toxicol Environ Health A. 2009;72(15-16):966-73. PMID: 19672765

Bernal MH, Solomon KR, Carrasquilla G. Toxicity of formulated glyphosate (glyphos) and cosmo-flux to larval Colombian frogs 1. Laboratory acute toxicity. J Toxicol Environ Health A. 2009;72(15-16):961-5. PMID: 19672764

Lushchak OV, Kubrak OI, Storey JM, Storey KB, Lushchak VI. Low toxic herbicide Roundup induces mild oxidative stress in goldfish tissues. Chemosphere. 2009 Aug;76(7):932-7. PMID: 19450865

Poletta GL, Larriera A, Kleinsorge E, Mudry MD. Genotoxicity of the herbicide formulation Roundup (glyphosate) in broad-snouted caiman (Caiman latirostris) evidenced by the Comet assay and the Micronucleus test. Mutat Res. 2009 Jan 31;672(2):95-102. PMID: 19022394

Cavalcante DG, Martinez CB, Sofia SH. Genotoxic effects of Roundup on the fish Prochilodus lineatus. Mutat Res. 2008 Aug-Sep;655(1-2):41-6. PMID:18638566

Costa MJ, Monteiro DA, Oliveira-Neto AL, Rantin FT, Kalinin AL. Oxidative stress biomarkers and heart function in bullfrog tadpoles exposed to Roundup Original. Ecotoxicology. 2008 Apr;17(3):153-63. PMID: 17987383

Langiano Vdo C, Martinez CB. Toxicity and effects of a glyphosate-based herbicide on the Neotropical fish Prochilodus lineatus. Comp Biochem Physiol C Toxicol Pharmacol. 2008 Mar;147(2):222-31. PMID: 17933590

 

Honeybees

Mengoni Goñalons C, Farina WM. Impaired associative learning after chronic exposure to pesticides in young adult honey bees. J Exp Biol. 2018 Apr 11;221(Pt 7). PMID: 29643175

Balbuena MS, Tison L, Hahn ML, Greggers U, Menzel R, Farina WM. Effects of sublethal doses of glyphosate on honeybee navigation. J Exp Biol. 2015 Sep;218(Pt 17):2799-805. PMID: 26333931

Sol Balbuena M, Tison L, Hahn ML, Greggers U, Menzel R, Farina WM. Effects of sub-lethal doses of glyphosate on honeybee navigation. J Exp Biol. 2015 Jul 10. PMID: 26163579

Herbert LT, Vázquez DE, Arenas A, Farina WM. Effects of field-realistic doses of glyphosate on honeybee appetitive behaviour. J Exp Biol. 2014 Oct 1;217(Pt 19):3457-64. PMID: 25063858

Helmer SH, Kerbaol A, Aras P, Jumarie C, Boily M. Effects of realistic doses of atrazine, metolachlor, and glyphosate on lipid peroxidation and diet-derived antioxidants in caged honey bees (Apis mellifera). Environ Sci Pollut Res Int. 2015 Jun;22(11):8010-21. PMID: 24728576

Thompson HM, Levine SL, Doering J, Norman S, Manson P, Sutton P, von Mérey G. Evaluating exposure and potential effects on honeybee brood (Apis mellifera) development using glyphosate as an example. Integr Environ Assess Manag. 2014 Jul;10(3):463-70. PMID: 24616275

 

Soil Microbiome

Hackenberger DK, Stjepanović N, Lončarić Ž, Hackenberger BK. Acute and subchronic effects of three herbicides on biomarkers and reproduction in earthworm Dendrobaena veneta. Chemosphere. 2018 Jun 6;208:722-730. PMID: 29894974

Zaller JG, Cantelmo C, Santos GD, Muther S, Gruber E, Pallua P, Mandl K, Friedrich B, Hofstetter I, Schmuckenschlager B, Faber F. Herbicides in vineyards reduce grapevine root mycorrhization and alter soil microorganisms and the nutrient composition in grapevine roots, leaves, xylem sap and grape juice. Environ Sci Pollut Res Int. 2018 Jun 3. PMID: 29862481

Liu Y, Li Y, Hua X, Müller K, Wang H, Yang T, Wang Q, Peng X, Wang M, Pang Y, Qi J, Yang Y. Glyphosate application increased catabolic activity of gram-negative bacteria but impaired soil fungal community. Environ Sci Pollut Res Int. 2018 May;25(15):14762-14772. PMID: 29541980

Lu GH, Hua XM, Cheng J, Zhu YL, Wang GH, Pang YJ, Yang RW, Zhang L, Shou H, Wang XM, Qi J, Yang YH. Impact of Glyphosate on the Rhizosphere Microbial Communities of An EPSPS-Transgenic Soybean Line ZUTS31 by Metagenome Sequencing. Curr Genomics. 2018 Jan;19(1):36-49. PMID: 29491731

Niemeyer JC, de Santo FB, Guerra N, Ricardo Filho AM, Pech TM. Do recommended doses of glyphosate-based herbicides affect soil invertebrates? Field and laboratory screening tests to risk assessment. Chemosphere. 2018 May;198:154-160. PMID: 29421725

Dennis PG, Kukulies T, Forstner C, Orton TG, Pattison AB. The effects of glyphosate, glufosinate, paraquat and paraquat-diquat on soil microbial activity and bacterial, archaeal and nematode diversity. Sci Rep. 2018 Feb 1;8(1):2119. PMID: 29391493

Wang C, Lin X, Li L, Lin L, Lin S. Glyphosate Shapes a Dinoflagellate-Associated Bacterial Community While Supporting Algal Growth as Sole Phosphorus Source. Front Microbiol. 2017 Dec 19;8:2530. PMID: 29312222

Schlatter DC, Yin C, Burke I, Hulbert S, Paulitz T. Location, Root Proximity, and Glyphosate-Use History Modulate the Effects of Glyphosate on Fungal Community Networks of Wheat. Microb Ecol. 2017 Dec 7. PMID: 29218372

Smedbol É, Gomes MP, Paquet S, Labrecque M, Lepage L, Lucotte M, Juneau P. Effects of low concentrations of glyphosate-based herbicide factor 540_® on an agricultural stream freshwater phytoplankton community. Chemosphere. 2018 Feb;192:133-141. PMID: 29100121

la Cecilia D, Maggi F. Analysis of glyphosate degradation in a soil microcosm. Environ Pollut. 2018 Feb;233:201-207. PMID: 29078124

Carranza CS, Barberis CL, Chiacchiera SM, Magnoli CE. Assessment of growth of Aspergillus spp. from agricultural soils in the presence of glyphosate. Rev Argent Microbiol. 2017 Oct – Dec;49(4):384-393. PMID: 28882409

Zhang Q, Zhou H, Li Z, Zhu J, Zhou C, Zhao M. Effects of glyphosate at environmentally relevant concentrations on the growth of and microcystin production by Microcystis aeruginosa. Environ Monit Assess. 2016 Nov;188(11):632. PMID: 27771872

Anza M, Epelde L, Artetxe U, Becerril JM, Garbisu C. Control of Cortaderia selloana with a glyphosate-based herbicide led to a short-term stimulation of soil fungal communities. Environ Monit Assess. 2016 Nov;188(11):631. PMID: 27770349

Nicolas V, Oestreicher N, Vélot C. Multiple effects of a commercial Roundup formulation on the soil filamentous fungus Aspergillus nidulans at low doses: evidence of an unexpected impact on energetic metabolism. Environ Sci Pollut Res Int. 2016 Jul;23(14):14393-404. PMID: 27068896

Newman MM, Lorenz N, Hoilett N, Lee NR, Dick RP, Liles MR, Ramsier C, Kloepper JW. Changes in rhizosphere bacterial gene expression following glyphosate treatment. Sci Total Environ. 2016 May 15;553:32-41. PMID: 26901800

Salvio C, Menone ML, Rafael S, Iturburu FG, Manetti PL. Survival, Reproduction, Avoidance Behavior and Oxidative Stress Biomarkers in the Earthworm Octolasion cyaneum Exposed to Glyphosate. Bull Environ Contam Toxicol. 2016 Mar;96(3):314-9. PMID: 26754543

Newman MM, Hoilett N, Lorenz N, Dick RP, Liles MR, Ramsier C, Kloepper JW. Glyphosate effects on soil rhizosphere-associated bacterial communities. Sci Total Environ. 2016 Feb 1;543(Pt A):155-60. PMID: 26580738

Pizarro H, Vera MS, Vinocur A, Pérez G, Ferraro M, Menéndez Helman RJ, Dos Santos Afonso M. Glyphosate input modifies microbial community structure in clear and turbid freshwater systems. Environ Sci Pollut Res Int. 2016 Mar;23(6):5143-53. PMID: 26552793

Carranza CS, Barberis CL, Chiacchiera SM, Dalcero AM, Magnoli CE. Isolation of culturable mycobiota from agricultural soils and determination of tolerance to glyphosate of nontoxigenic Aspergillus section Flavi strains. J Environ Sci Health B. 2016;51(1):35-43. PMID: 26549415

Gaupp-Berghausen M, Hofer M, Rewald B, Zaller JG. Glyphosate-based herbicides reduce the activity and reproduction of earthworms and lead to increased soil nutrient concentrations. Sci Rep. 2015 Aug 5;5:12886. PMID: 26243044

Buck JC, Hua J, Brogan WR 3rd, Dang TD, Urbina J, Bendis RJ, Stoler AB, Blaustein AR, Relyea RA. Effects of Pesticide Mixtures on Host-Pathogen Dynamics of the Amphibian Chytrid Fungus. PLoS One. 2015 Jul 16;10(7):e0132832. PMID: 26181492

Zabaloy MC, Carné I, Viassolo R, Gómez MA, Gomez E. Soil ecotoxicity assessment of glyphosate use under field conditions: microbial activity and community structure of Eubacteria and ammonia-oxidising bacteria. Pest Manag Sci. 2016 Apr;72(4):684-91. PMID: 25960311

Lima IS, Baumeier NC, Rosa RT, Campelo PM, Rosa EA. Influence of glyphosate in planktonic and biofilm growth of Pseudomonas aeruginosa. Braz J Microbiol. 2014 Oct 9;45(3):971-5. PMID: 25477933

Zhou CF, Wang YJ, Sun RJ, Liu C, Fan GP, Qin WX, Li CC, Zhou DM. Inhibition effect of glyphosate on the acute and subacute toxicity of cadmium to earthworm Eisenia fetida. Environ Toxicol Chem. 2014 Oct;33(10):2351-7. PMID: 25043609

Carranza CS, Bergesio MV, Barberis CL, Chiacchiera SM, Magnoli CE. Survey of Aspergillus section Flavi presence in agricultural soils and effect of glyphosate on nontoxigenic A. flavus growth on soil-based medium. J Appl Microbiol. 2014 May;116(5):1229-40. PMID: 24428372

Barberis CL, Carranza CS, Chiacchiera SM, Magnoli CE. Influence of herbicide glyphosate on growth and aflatoxin B1 production by Aspergillus section Flavi strains isolated from soil on in vitro assay. J Environ Sci Health B. 2013;48(12):1070-9. PMID: 24007484

Muangphra P, Kwankua W, Gooneratne R. Genotoxic effects of glyphosate or paraquat on earthworm coelomocytes. Environ Toxicol. 2014 Jun;29(6):612-20. PMID: 22644885

Barriuso J, Mellado RP. Relative effect of glyphosate on glyphosate-tolerant maize rhizobacterial communities is not altered by soil properties. J Microbiol Biotechnol. 2012 Feb;22(2):159-65. PMID: 22370343

Clair E, Linn L, Travert C, Amiel C, Séralini GE, Panoff JM. Effects of Roundup and glyphosate on three food microorganisms: Geotrichum candidum, Lactococcus lactis subsp. cremoris and Lactobacillus delbrueckii subsp. bulgaricus. Curr Microbiol. 2012 May;64(5):486-91. PMID: 22362186

Zhou CF, Wang YJ, Yu YC, Sun RJ, Zhu XD, Zhang HL, Zhou DM. Does glyphosate impact on Cu uptake by, and toxicity to, the earthworm Eisenia fetida? Ecotoxicology. 2012 Nov;21(8):2297-305. PMID: 22975893

Lo CC. Effect of pesticides on soil microbial community. J Environ Sci Health B. 2010 Jul;45(5):348-59. PMID: 20512724

Pereira JL, Antunes SC, Castro BB, Marques CR, Gonçalves AM, Gonçalves F, Pereira R. Toxicity evaluation of three pesticides on non-target aquatic and soil organisms: commercial formulation versus active ingredient. Ecotoxicology. 2009 May;18(4):455-63. PMID: 19205879

Stachowski-Haberkorn S, Becker B, Marie D, Haberkorn H, Coroller L, de la Broise D. Impact of Roundup on the marine microbial community, as shown by an in situ microcosm experiment. Aquat Toxicol. 2008 Sep 29;89(4):232-41. PMID: 18760491

Sailaja KK, Satyaprasad K. Degradation of glyphosate in soil and its effect on fungal population. J Environ Sci Eng. 2006 Jul;48(3):189-90. PMID: 17915782

 

Physiological Testing

Connolly A, Leahy M, Jones K, Kenny L, Coggins MA. Glyphosate in Irish adults – A pilot study in 2017. Environ Res. 2018 Aug;165:235-236. PMID: 29729481

Mills PJ, Kania-Korwel I, Fagan J, McEvoy LK, Laughlin GA, Barrett-Connor E. Excretion of the Herbicide Glyphosate in Older Adults Between 1993 and 2016. JAMA. 2017 Oct 24;318(16):1610-1611. PMID: 29067413

Kongtip P, Nankongnab N, Phupancharoensuk R, Palarach C, Sujirarat D, Sangprasert S, Sermsuk M, Sawattrakool N, Woskie SR. Glyphosate and Paraquat in Maternal and Fetal Serums in Thai Women. J Agromedicine. 2017;22(3):282-289. PMID: 28422580

Knudsen LE, Hansen PW, Mizrak S, Hansen HK, Mørck TA, Nielsen F, Siersma V, Mathiesen L. Biomonitoring of Danish school children and mothers including biomarkers of PBDE and glyphosate. Rev Environ Health. 2017 Sep 26;32(3):279-290. PMID: 28306542

Conrad A, Schröter-Kermani C, Hoppe HW, Rüther M, Pieper S, Kolossa-Gehring M. Glyphosate in German adults – Time trend (2001 to 2015) of human exposure to a widely used herbicide. Int J Hyg Environ Health. 2017 Jan;220(1):8-16. PMID: 27838355

McGuire MK, McGuire MA, Price WJ, Shafii B, Carrothers JM, Lackey KA, Goldstein DA, Jensen PK, Vicini JL. Glyphosate and aminomethylphosphonic acid are not detectable in human milk. Am J Clin Nutr. 2016 May;103(5):1285-90. PMID: 27030536Steinborn A, Alder L, Michalski B, Zomer P, Bendig P, Martinez SA, Mol HG, Class TJ, Pinheiro NC. Determination of Glyphosate Levels in Breast Milk Samples from Germany by LC-MS/MS and GC-MS/MS. J Agric Food Chem. 2016 Feb 17;64(6):1414-21. PMID: 26808680

Bus JS. Analysis of Moms Across America report suggesting bioaccumulation of glyphosate in U.S. mother’s breast milk: Implausibility based on inconsistency with available body of glyphosateanimal toxicokinetic, human biomonitoring, and physico-chemical data. Regul Toxicol Pharmacol. 2015 Dec;73(3):758-64. PMID: 26520181

Mesnage R, Defarge N, Spiroux de Vendômois J, Séralini GE. Major pesticides are more toxic to human cells than their declared active principles. Biomed Res Int. 2014;2014:179691. PMID: 24719846

Zouaoui K, Dulaurent S, Gaulier JM, Moesch C, Lachâtre G. Determination of glyphosate and AMPA in blood and urine from humans: about 13 cases of acute intoxication. Forensic Sci Int. 2013 Mar 10;226(1-3):e20-5. PMID: 23291146

McQueen H, Callan AC, Hinwood AL. Estimating maternal and prenatal exposure to glyphosate in the community setting. Int J Hyg Environ Health. 2012 Nov;215(6):570-6. PMID: 22261298

 

Food Contamination

Jansons M, Pugajeva I, Bartkevičs V. Occurrence of glyphosate in beer from the Latvian market. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 May 2. PMID: 29718772

Rodrigues NR, de Souza APF. Occurrence of glyphosate and AMPA residues in soy-based infant formula sold in Brazil. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Apr;35(4):723-730. PMID: 29267136

Stephenson CL, Harris CA, Clarke R. An assessment of the acute dietary exposure to glyphosate using deterministic and probabilistic methods. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Feb;35(2):258-272. PMID: 29052491

Van Eenennaam AL, Young AE. Detection of dietary DNA, protein, and glyphosate in meat, milk, and eggs. J Anim Sci. 2017 Jul;95(7):3247-3269. PMID: 28727079

Simonetti E, Cartaud G, Quinn RM, Marotti I, Dinelli G. An Interlaboratory Comparative Study on the Quantitative Determination of Glyphosate at Low Levels in Wheat Flour. J AOAC Int. 2015 Nov-Dec;98(6):1760-8.  PMID: 26651590

 

Detoxification

Fu GM, Chen Y, Li RY, Yuan XQ, Liu CM, Li B, Wan Y. Pathway and rate-limiting step of glyphosate degradation by Aspergillus oryzae A-F02. Prep Biochem Biotechnol. 2017 Sep 14;47(8):782-788. PMID: 28636478

Rebai O, Belkhir M, Boujelben A, Fattouch S, Amri M. Morus alba leaf extract mediates neuroprotection against glyphosate-induced toxicity and biochemical alterations in the brain. Environ Sci Pollut Res Int. 2017 Apr;24(10):9605-9613. PMID: 28247273

Arroyave JM, Waiman CC, Zanini GP, Avena MJ. Effect of humic acid on the adsorption/desorption behavior of glyphosate on goethite. Isotherms and kinetics. Chemosphere. 2016 Feb;145:34-41. PMID: 26657085

Alleva R, Manzella N, Gaetani S, Ciarapica V, Bracci M, Caboni MF, Pasini F, Monaco F, Amati M, Borghi B, Tomasetti M. Organic honey supplementation reverses pesticide-induced genotoxicity by modulating DNA damage response. Mol Nutr Food Res. 2016 Oct;60(10):2243-2255. PMID: 27129605

Carneiro RT, Taketa TB, Gomes Neto RJ, Oliveira JL, Campos EV, de Moraes MA, da Silva CM, Beppu MM, Fraceto LF. Removal of glyphosate herbicide from water using biopolymer membranes. J Environ Manage. 2015 Mar 15;151:353-60. PMID: 25585148

Nakae H, Kusanagi M, Okuyama M, Igarashi T. Paralytic ileus induced by glyphosate intoxication successfully treated using Kampo medicine. Acute Med Surg. 2014 Dec 11;2(3):214-218. PMID: 29123725

Givaudan N, Binet F, Le Bot B, Wiegand C. Earthworm tolerance to residual agricultural pesticide contamination: field and experimental assessment of detoxification capabilities. Environ Pollut. 2014 Sep;192:9-18. PMID: 24874794

Shehata AA, Kühnert M, Haufe S, Krüger M. Neutralization of the antimicrobial effect of glyphosate by humic acid in vitro. Chemosphere. 2014 Jun;104:258-61. PMID: 24268342

Astiz M, de Alaniz MJ, Marra CA. The oxidative damage and inflammation caused by pesticides are reverted by lipoic acid in rat brain. Neurochem Int. 2012 Dec;61(7):1231-41. PMID: 22995786

Cavuşoğlu K, Yapar K, Oruç E, Yalçın E. Protective effect of Ginkgo biloba L. leaf extract against glyphosate toxicity in Swiss albino mice. J Med Food. 2011 Oct;14(10):1263-72. PMID: 21859351

Klimek M, Lejczak B, Kafarski P, Forlani G. Metabolism of the phosphonate herbicide glyphosate by a non-nitrate-utilizing strain of Penicillium chrysogenum. Pest Manag Sci. 2001 Sep;57(9):815-21. PMID: 11561407

 

Adjuvant Effects

Mesnage R, Antoniou MN. Ignoring Adjuvant Toxicity Falsifies the Safety Profile of Commercial Pesticides. Front Public Health. 2018 Jan 22;5:361. PMID: 29404314

Chaufan G, Coalova I, Ríos de Molina Mdel C. Glyphosate commercial formulation causes cytotoxicity, oxidative effects, and apoptosis on human cells: differences with its active ingredient. Int J Toxicol. 2014 Jan-Feb;33(1):29-38. PMID: 24434723