Penitrem A – Screening Tests

 

 

This page lists medical journal articles discussing screening tests for penitrem A.

The Health Effects of Penitrem A page of the Paradigm Change site provides further information on the effects of this mycotoxin.

 

Kalinina SA, Jagels A, Hickert S, Mauriz Marques LM, Cramer B, Humpf HU. Detection of the Cytotoxic Penitrems A-F in Cheese from the European Single Market by HPLC-MS/MS. J Agric Food Chem. 2018 Feb 7;66(5):1264-1269. PMID: 29338236

Several cases of intoxications with penitrems and subsequent occurrences of penitrem A in foodstuff underline the need for reliable quantitation methods for the detection of these mycotoxins in food. In this study, a simple and fast high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method for the quantitative analysis of penitrems A-F in cheese was developed. Moreover, we report cytotoxic effects of all penitrems on two cell lines (HepG2 and CCF-STTG1).

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Maragos C. M.. Photoreaction of indole-containing mycotoxins to fluorescent products. Mycotoxin research. 2009;25:67–75.

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Tiwary Asheesh K., Puschner Birgit, Poppenga Robert H.. Using roquefortine C as a biomarker for penitrem A intoxication. Journal of veterinary diagnostic investigation. 2009;21:237–239.

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Tor Elizabeth R., Puschner Birgit, Filigenzi Michael S., Tiwary Asheesh K., Poppenga Robert H.. LC-MS/MS screen for penitrem A and roquefortine C in serum and urine samples. Analytical chemistry. 2006;78:4624–4629.

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Braselton W. Emmett, Johnson Malgorzata. Thin layer chromatography convulsant screen extended by gas chromatography-mass spectrometry. Journal of veterinary diagnostic investigation. 2003;15:42–45.

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Braselton W. E., Rumler P. C.. MS/MS screen for the tremorgenic mycotoxins roquefortine and penitrem A. Journal of veterinary diagnostic investigation. 1996;8:515– 518.

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Frisvad J. C., Thrane U.. Standardized high-performance liquid chromatography of 182 mycotoxins and other fungal metabolites based on alkylphenone retention indices and UV-VIS spectra (diode array detection). Journal of chromatography. 1987;404:195– 214.

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Gimeno A.. Thin layer chromatographic determination of aflatoxins, ochratoxins, sterigmatocystin, zearalenone, citrinin, T-2 toxin, diacetoxyscirpenol, penicillic acid, patulin, and penitrem A. Journal – Association of Official Analytical Chemists. 1979;62:579–585.

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Roberts B. A., Patterson D. S.. Detection of twelve mycotoxins in mixed animal feedstuffs, using a novel membrane cleanup procedure. Journal – Association of Official Analytical Chemists. 1975;58:1178–1181.

 

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