Fusarium Literature – Animal Studies

 

 

Various

Broekaert N, Devreese M, van Bergen T, Schauvliege S, De Boevre M, De Saeger S, Vanhaecke L, Berthiller F, Michlmayr H, Malachová A, Adam G, Vermeulen A, Croubels S. In vivo contribution of deoxynivalenol-3-β-D-glucoside to deoxynivalenol exposure in broiler chickens and pigs: oral bioavailability, hydrolysis and toxicokinetics. Arch Toxicol. 2017 Feb;91(2):699-712. PMID: 27100115

Döll Susanne, Dänicke Sven. The Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) in animal feeding. Preventive veterinary medicine.  2011;102:132–145.

Jarvis B. B., Wang S., Cox C., et al. Brazilian Baccharis toxins: livestock poisoning and the isolation of macrocyclic trichothecene glucosides.  Natural toxins.  1996;4:58–71.

Cheeke P. R.. Endogenous toxins and mycotoxins in forage grasses and their effects on livestock. Journal of animal science.  1995;73:909–918.

Schiefer H. B.. Mycotoxicoses of domestic animals and their diagnosis.  Canadian journal of physiology and pharmacology.  1990;68:987–990.

Trenholm H. L., Hamilton R. M., Friend D. W., Thompson B. K., Hartin K. E.. Feeding trials with vomitoxin (deoxynivalenol)-contaminated wheat: effects on swine, poultry, and dairy cattle. Journal of the American Veterinary Medical Association.  1984;185:527–531.

Jodczyk K. J.. [Effect of nitrogen derivative of verrucarin E, VER-I, on biology and development of morphological, histochemical and histoenzymatic changes in experimental neoplasms in animals]. Patologia polska.  1984;35:349–364.

Trenholm H. L., Cochrane W. P., Cohen H., et al. Survey of vomitoxin contamination of 1980 Ontario white winter wheat crop: results of survey and feeding trials. Journal – Association of Official Analytical Chemists.  1983;66:92–97.

Pier A. C., Richard J. L., Cysewski S. J.. Implications of mycotoxins in animal disease. Journal of the American Veterinary Medical Association.  1980;176:719–724.

Harwig J., Munro I. C.. Mycotoxins of possible importance in diseases of Canadian farm animals. The Canadian veterinary journal. La revue vétérinaire canadienne.  1975;16:125–141.

 

Mammals

Schwartz-Zimmermann HE, Hametner C, Nagl V, Fiby I, Macheiner L, Winkler J, Dänicke S, Clark E, Pestka JJ, Berthiller F. Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows. Arch Toxicol. 2017 Jun 21. PMID: 28638985

Gajęcka M, Tarasiuk M, Zielonka Ł, Dąbrowski M, Nicpoń J, Baranowski M, Gajęcki MT. Changes in the metabolic profile and body weight of pre-pubertal gilts during prolonged monotonic exposure to low doses of zearalenone and deoxynivalenol. Toxicon. 2017 Jan;125:32-43. PMID: 27840141

Dänicke S, Winkler J, Meyer U, Frahm J, Kersten S. Haematological, clinical-chemical and immunological consequences of feeding Fusarium toxin contaminated diets to early lactating dairy cows. Mycotoxin Res. 2017 Feb;33(1):1-13. PMID: 27830510

Ji J, Zhu P, Cui F, Pi F, Zhang Y, Sun X. The disorder metabolic profiling in kidney and spleen of mice induced by mycotoxins deoxynivalenol through gas chromatography mass spectrometry. Chemosphere. 2017 Aug;180:267-274. PMID: 28411543

Golder HM, Moss N, Rogers G, Jackson B, Gannon N, Wong P, Lean IJ. Acute photosensitisation and mortality in a herd of dairy cattle in Tasmania. N Z Vet J. 2017 Jan;65(1):39-45. PMID: 27593392

Kovács M, Pósa R, Tuboly T, Donkó T, Repa I, Tossenberger J, Szabó-Fodor J, Stoev S, Magyar T. Feed exposure to FB1 can aggravate pneumonic damages in pigs provoked by P. multocida. Res Vet Sci. 2016 Oct;108:38-46. PMID: 27663368

Bondy GS, Coady L, Curran I, Caldwell D, Armstrong C, Aziz SA, Nunnikhoven A, Gannon AM, Liston V, Shenton J, Mehta R. Effects of chronic deoxynivalenol exposure on p53 heterozygous and p53 homozygous mice. Food Chem Toxicol. 2016 Oct;96:24-34. PMID: 27456127

Lessard M, Savard C, Deschene K, Lauzon K, Pinilla VA, Gagnon CA, Lapointe J, Guay F, Chorfi Y. Impact of deoxynivalenol (DON) contaminated feed on intestinal integrity and immune response in swine. Food Chem Toxicol. 2015 Jun;80:7-16. PMID: 25701311

Pizzo F, Caloni F, Schreiber NB, Cortinovis C, Spicer LJ. In vitro effects of deoxynivalenol and zearalenone major metabolites alone and combined, on cell proliferation, steroid production and gene expression in bovine small-follicle granulosa cells. Toxicon. 2016 Jan;109:70-83. PMID: 26657070

Dänicke S, Meyer U, Winkler J, Ulrich S, Frahm J, Kersten S, Valenta H, Rehage J, Häussler S, Sauerwein H, Locher L. Haematological and immunological adaptations of non-pregnant, non-lactating dairy cows to a high-energetic diet containing mycotoxins. Arch Anim Nutr. 2016;70(1):1-16. PMID: 26654380

Jovaišienė J, Bakutis B, Baliukonienė V, Gerulis G. Fusarium and Aspergillus mycotoxins effects on dairy cow health, performance and the efficacy of Anti-Mycotoxin Additive. Pol J Vet Sci. 2016;19(1):79-87. PMID: 27096791

Saint-Cyr MJ, Perrin-Guyomard A, Manceau J, Houée P, Delmas JM, Rolland JG, Laurentie M. Risk Assessment of Deoxynivalenol by Revisiting Its Bioavailability in Pig and Rat Models to Establish Which Is More Suitable. Toxins (Basel). 2015 Dec 1;7(12):5167-81. PMID: 26633505

Albonico M, Schütz LF, Caloni F, Cortinovis C, Spicer LJ. Toxicological effects of fumonisin B1 alone and in combination with other fusariotoxins on bovine granulosa cells. Toxicon. 2016 Aug;118:47-53. PMID: 27108238

Szabó A, Szabó-Fodor J, Fébel H, Mézes M, Bajzik G, Kovács M. Oral administration of fumonisin B1 and T-2 individually and in combination affects hepatic total and mitochondrial membrane lipid profile of rabbits. Physiol Int. 2016 Sep;103(3):321-333. PMID: 28229635

Pósa R, Stoev S, Kovács M, Donkó T, Repa I, Magyar T. A comparative pathological finding in pigs exposed to fumonisin B1 and/or Mycoplasma hyopneumoniae. Toxicol Ind Health. 2016 Jun;32(6):998-1012. PMID: 25107460

Obremski K, Gonkowski S, Wojtacha P. Zearalenone-induced changes in the lymphoid tissue and mucosal nerve fibers in the porcine ileum. Pol J Vet Sci. 2015;18(2):357-65. PMID: 26172186

Wu L, Liao P, He L, Ren W, Yin J, Duan J, Li T. Growth performance, serum biochemical profile, jejunal morphology, and the expression of nutrients transporter genes in deoxynivalenol (DON)- challenged growing pigs. BMC Vet Res. 2015 Jul 3;11:144. PMID: 26138080

Śliżewska K, Nowak A, Piotrowska M, Żakowskax Z, Gajęcka M, Zielonka Ł, Gajęcki M. Cecal enzyme activity in gilts following experimentally induced Fusariummycotoxicosis. Pol J Vet Sci. 2015;18(1):191-7. PMID: 25928927

Brzuzan P, Woźny M, Wolińska-Nizioł L, Piasecka A, Florczyk M, Jakimiuk E, Góra M, Łuczyński MK, Gajecki M. MicroRNA expression profiles in liver and colon of sexually immature gilts after exposure to Fusarium mycotoxins. Pol J Vet Sci. 2015;18(1):29-38. PMID: 25928907

Kong C, Shin SY, Park CS, Kim BG. Effects of Feeding Barley Naturally Contaminated with Fusarium Mycotoxins on Growth Performance, Nutrient Digestibility, and Blood Chemistry of Gilts and Growth Recoveries by Feeding a Non-contaminated Diet. Asian-Australas J Anim Sci. 2015 May;28(5):662-70. PMID: 25715687

Winkler J, Kersten S, Meyer U, Stinshoff H, Locher L, Rehage J, Wrenzycki C, Engelhardt UH, Dänicke S. Diagnostic opportunities for evaluation of the exposure of dairy cows to the mycotoxins deoxynivalenol (DON) and zearalenone (ZEN): reliability of blood plasma, bile and follicular fluid as indicators. J Anim Physiol Anim Nutr (Berl). 2015 Oct;99(5):847-55. PMID: 25556890

Jonsson M, Atosuo J, Jestoi M, Nathanail AV, Kokkonen UM, Anttila M, Koivisto P, Lilius EM, Peltonen K. Repeated dose 28-day oral toxicity study of moniliformin in rats. Toxicol Lett. 2015 Feb 17;233(1):38-44. PMID: 25482064

Demirel G, Alpertunga B, Ozden S. Role of fumonisin B1 on DNA methylation changes in rat kidney and liver cells. Pharm Biol. 2015;53(9):1302-10. PMID: 25858139

Hahn I, Nagl V, Schwartz-Zimmermann HE, Varga E, Schwarz C, Slavik V, Reisinger N, Malachová A, Cirlini M, Generotti S, Dall’Asta C, Krska R, Moll WD, Berthiller F. Effects of orally administered fumonisin B₁ (FB₁), partially hydrolysed FB₁, hydrolysed FB₁ and N-(1-deoxy-D-fructos-1-yl) FB₁ on the sphingolipid metabolism in rats. Food Chem Toxicol. 2015 Feb;76:11-8. PMID: 25475052

Gerez JR, Pinton P, Callu P, Grosjean F, Oswald IP, Bracarense AP. Deoxynivalenol alone or in combination with nivalenol and zearalenone induce systemic histological changes in pigs. Exp Toxicol Pathol. 2015 Feb;67(2):89-98. PMID: 25467749

Mukherjee D, Royce SG, Alexander JA, Buckley B, Isukapalli SS, Bandera EV, Zarbl H, Georgopoulos PG. Physiologically-based toxicokinetic modeling of zearalenone and its metabolites: application to the Jersey girl study. PLoS One. 2014 Dec 4;9(12):e113632. PMID: 25474635

Stopa E, Gajęcka M, Babińska I, Zielonka L, Gajęcki M. The effect of experimental exposure to low doses of zearalenone on uterine histology and morphometry in prepubertal bitches. Theriogenology. 2014 Sep 1;82(4):537-45. PMID: 25001979

Chandratre GA, Telang AG, Badgujar PC, Raut SS, Sharma AK. Toxicopathological alterations induced by high dose dietary T-2 mycotoxin and its residue detection in Wistar rats. Arch Environ Contam Toxicol. 2014 Jul;67(1):124-38. PMID: 24553812

Tardivel C, Airault C, Djelloul M, Guillebaud F, Barbouche R, Troadec JD, Gaigé S, Dallaporta M. The food born mycotoxin deoxynivalenol induces low-grade inflammation in mice in the absence of observed-adverse effects. Toxicol Lett. 2015 Feb 3;232(3):601-11. PMID: 25549547

Savard C, Pinilla V, Provost C, Segura M, Gagnon CA, Chorfi Y. In vitro effect of deoxynivalenol (DON) mycotoxin on porcine reproductive and respiratory syndrome virus replication. Food Chem Toxicol. 2014 Mar;65:219-26. PMID: 24394488

Savard C, Pinilla V, Provost C, Gagnon CA, Chorfi Y. In vivo effect of deoxynivalenol (DON) naturally contaminated feed on porcine reproductive and respiratory syndrome virus (PRRSV) infection. Vet Microbiol. 2014 Dec 5;174(3-4):419-26. PMID: 25465662

Boeira SP, Filho CB, Del’Fabbro L, Roman SS, Royes LF, Fighera MR, Jessé CR, Oliveira MS, Furian AF. Damage induced by acute zearalenone administration in male Swiss mice. Exp Toxicol Pathol. 2014 Jul;66(4):179-85. PMID: 24503513

Saengtienchai T, Poapolathep S, Isariyodom S, Ikenaka Y, Ishizuka M, Poapolathep A. Toxicokinetics and tissue depletion of Fusarenon-X and its metabolite nivalenol in piglets. Food Chem Toxicol. 2014 Apr;66:307-12. PMID: 24508584

Brezina U, Rempe I, Kersten S, Valenta H, Humpf HU, Dänicke S. Diagnosis of intoxications of piglets fed with Fusarium toxin-contaminated maize by the analysis of mycotoxin residues in serum, liquor and urine with LC-MS/MS.Arch Anim Nutr. 2014 Dec;68(6):425-47. PMID: 25355041

Dänicke S, Keese C, Meyer U, Starke A, Kinoshita A, Rehage J. Zearalenone (ZEN) metabolism and residue concentrations in physiological specimens of dairy cows exposed long-term to ZEN-contaminated diets differing in concentrate feed proportions. Arch Anim Nutr. 2014 Dec;68(6):492-506. PMID: 25348458

Cheng G, Liu C, Wang X, Ma H, Pan Y, Huang L, Hao H, Dai M, Yuan Z. Structure-function analysis of porcine cytochrome P450 3A29 in the hydroxylation of T-2 toxin as revealed by docking and mutagenesis studies. PLoS One. 2014 Sep 3;9(9):e106769. PMID: 25184434

Winkler J, Kersten S, Meyer U, Engelhardt U, Dänicke S. Residues of zearalenone (ZEN), deoxynivalenol (DON) and their metabolites in plasma of dairy cows fed Fusarium contaminated maize and their relationships to performance parameters. Food Chem Toxicol. 2014 Mar;65:196-204. PMID: 24361404

Li S, Blain EJ, Cao J, Caterson B, Duance VC. Effects of the mycotoxin nivalenol on bovine articular chondrocyte metabolism in vitro. PLoS One. 2014 Oct 15;9(10):e109536. PMID: 25329658

Manyes L, Escrivá L, Serrano AB, Rodríguez-Carrasco Y, Tolosa J, Meca G, Font G. A preliminary study in Wistar rats with enniatin A contaminated feed. Toxicol Mech Methods. 2014 Mar;24(3):179-90. PMID: 24329503

Kovács Melinda, Tornyos Gábor, Matics Zsolt, et al. Effect of chronic T-2 toxin exposure in rabbit bucks, determination of the No Observed Adverse Effect Level (NOAEL). Animal reproduction science.  2013;137:245–252.

Kouadio JH, Moukha S, Brou K, Gnakri D. Lipid metabolism disorders, lymphocytes cells death, and renal toxicity induced by very low levels of deoxynivalenol and fumonisin b1 alone or in combination following 7 days oral administration to mice. Toxicol Int. 2013 Sep;20(3):218-23. PMID: 24403731

Ferreras M. C., Benavides J., García-Pariente C., et al. Acute and chronic disease associated with naturally occurring T-2 mycotoxicosis in sheep.  Journal of comparative pathology.  2013;148:236–242.

Rempe Inga, Brezina Ulrike, Kersten Susanne, Dänicke Sven. Effects of a Fusarium toxin-contaminated maize treated with sodium metabisulphite, methylamine and calcium hydroxide in diets for female piglets. Archives of animal nutrition.  2013;67:314–329.

Marczuk J., Obremski K., Lutnicki K., Gajecka M., Gajecki M.. Zearalenone and deoxynivalenol mycotoxicosis in dairy cattle herds. Polish journal of veterinary sciences.  2012;15:365–372.

Caloni Francesca, Cortinovis Cristina. Effects of fusariotoxins in the equine species. Veterinary journal (London, England : 1997).  2010;186:157–161.

Mikami Osamu, Yamaguchi Hiroyuki, Murata Hideo, Nakajima Yasuyuki, Miyazaki Shigeru. Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets. Journal of veterinary science.  2010;11:107–113.

Corps Kara N., Islam Zahidul, Pestka James J., Harkema Jack R.. Neurotoxic, inflammatory, and mucosecretory responses in the nasal airways of mice repeatedly exposed to the macrocyclic trichothecene mycotoxin roridin A: dose-response and persistence of injury. Toxicologic pathology.  2010;38:429–451.

Jakovac-Strajn B., Vengust A., Pestevsek U.. Effects of a deoxynivalenol-contaminated diet on the reproductive performance and immunoglobulin concentrations in pigs. The Veterinary record.  2009;165:713–718.

Zielonka ł., Wiśniewska M., Gajecka M., Obremski K., Gajecki M.. Influence of low doses of deoxynivalenol on histopathology of selected organs of pigs. Polish journal of veterinary sciences.  2009;12:89–95.

Takahashi Miwa, Shibutani Makoto, Sugita-Konishi Yoshiko, et al. A 90-day subchronic toxicity study of nivalenol, a trichothecene mycotoxin, in F344 rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  2008;46:125–135.

Sugita-Konishi Y., Kubosaki A., Takahashi M., et al. Nivalenol and the targeting of the female reproductive system as well as haematopoietic and immune systems in rats after 90-day exposure through the diet. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.  2008;25:1118–1127.

Chen Feng, Ma Yulin, Xue Chunyi, et al. The combination of deoxynivalenol and zearalenone at permitted feed concentrations causes serious physiological effects in young pigs. Journal of veterinary science.  2008;9:39–44.

Gutzwiller A., Czeglédi L., Stoll P., Bruckner L.. Effects of Fusarium toxins on growth, humoral immune response and internal organs in weaner pigs, and the efficacy of apple pomace as an antidote. Journal of animal physiology and animal nutrition.  2007;91:432–438.

Korosteleva S. N., Smith T. K., Boermans H. J.. Effects of feedborne Fusarium mycotoxins on the performance, metabolism, and immunity of dairy cows.  Journal of dairy science.  2007;90:3867–3873.

Döll Susanne, Goyarts Tanja, Tiemann Ute, Dänicke Sven. Practically relevant concentrations of deoxynivalenol in diets for growing-finishing pigs offered as mash or pellets. Archives of animal nutrition.  2007;61:247–265.

Accensi F., Pinton P., Callu P., et al. Ingestion of low doses of deoxynivalenol does not affect hematological, biochemical, or immune responses of piglets. Journal of animal science.  2006;84:1935–1942.

Cetin Y., Bullerman L. B.. Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  2005;43:755–764.

Gouze M. E., Laffitte J., Dedieu G., et al. Individual and combined effects of low oral doses of deoxynivalenol and nivalenol in mice. Cellular and molecular biology (Noisy-le-Grand, France).  2005;51 Suppl.

Raymond S. L., Smith T. K., Swamy H. V.. Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on feed intake, metabolism, and indices of athletic performance of exercised horses. Journal of animal science.  2005;83:1267–1273.

Böhm J., Razzazi E.. Effects of feeding deoxynivalenol contaminated wheat to piglets. Mycotoxin research.  2003;19:176–179.

Hughes D. M., Gahl M. J., Graham C. H., Grieb S. L.. Overt signs of toxicity to dogs and cats of dietary deoxynivalenol. Journal of animal science.  1999;77:693–700.

Banotai C., Greene-McDowelle D. M., Azcona-Olivera J. I., Pestka J. J.. Effects of intermittent vomitoxin exposure on body weight, immunoglobulin levels and haematuria in the B6C3F1 mouse. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1999;37:343–350.

Johnson P. J., Casteel S. W., Messer N. T.. Effect of feeding deoxynivalenol (vomitoxin)-contaminated barley to horses. Journal of veterinary diagnostic investigation.  1997;9:219–221.

Velazco V., Faifer G. C., Godoy H. M.. Differential effects of T-2 toxin on bone marrow and spleen erythropoiesis in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1996;34:371–375.

Harvey R. B., Edrington T. S., Kubena L. F., Elissalde M. H., Corrier D. E., Rottinghaus G. E.. Effect of aflatoxin and diacetoxyscirpenol in ewe lambs. Bulletin of environmental contamination and toxicology.  1995;54:325–330.

Rotter B. A., Thompson B. K., Lessard M., Trenholm H. L., Tryphonas H.. Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine. Fundamental and applied toxicology.  1994;23:117–124.

Prelusky D. B., Gerdes R. G., Underhill K. L., Rotter B. A., Jui P. Y., Trenholm H. L.. Effects of low-level dietary deoxynivalenol on haematological and clinical parameters of the pig. Natural toxins.  1994;2:97–104.

Szilágyi M., Fekete S., Huszenicza G. Y., Albert M.. Biochemical and physiological effects of long-term sublethal T-2 toxin feeding in rabbits. Acta biologica Hungarica.  1994;45:69–76.

Charmley E., Trenholm H. L., Thompson B. K., et al. Influence of level of deoxynivalenol in the diet of dairy cows on feed intake, milk production, and its composition. Journal of dairy science.  1993;76:3580–3587.

Gulick P. J.. Could mycotoxins in Dutch pig-farming explain certain management problems? Tijdschrift voor diergeneeskunde.  1993;118.

Harvey R. B., Kubena L. F., Elissalde M. H., et al. Cocontamination of swine diets by aflatoxin and diacetoxyscirpenol. Journal of veterinary diagnostic investigation.  1991;3:155–160.

Creasia D. A., Thurman J. D., Wannemacher R. W., Bunner D. L.. Acute inhalation toxicity of T-2 mycotoxin in the rat and guinea pig. Fundamental and applied toxicology.  1990;14:54–59.

Palyusik M., Harrach B., Horvath G., Mirocha C. J.. Experimental fusariotoxicosis of swine produced by zearalenone and T-2 toxins.  Journal of environmental pathology, toxicology and oncology.  1990;10:52–55.

Middlebrook J. L., Leatherman D. L.. Specific association of T-2 toxin with mammalian cells. Biochemical pharmacology.  1989;38:3093–3102.

Yamamura H., Kobayashi T., Ryu J. C., et al. Subchronic feeding studies with nivalenol in C57BL/6 mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1989;27:585–590.

Middlebrook J. L., Leatherman D. L.. Differential association of T-2 and T-2 tetraol with mammalian cells. The Journal of pharmacology and experimental therapeutics.  1989;250:860–866.

Ohtsubo K., Ryu J. C., Nakamura K., et al. Chronic toxicity of nivalenol in female mice: a 2-year feeding study with Fusarium nivale Fn 2B-moulded rice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1989;27:591–598.

Bergmann F., Yarom R., Yagen B.. Comparison of the toxicity of two trichothecenes applied topically to brain and liver of rats. Toxicology letters.  1989;48:49–56.

Borison H. L., Goodheart M. L.. Neural factors in acute emetic, cardiovascular, and respiratory effects of T-2 toxin in cats. Toxicology and applied pharmacology.  1989;101:399–413.

Glávits R., Ványi A., Fekete S., Tamás J.. Acute toxicological experiment of T-2 toxin in rabbits. Acta veterinaria Hungarica.  1989;37:75–79.

Niyo K. A., Richard J. L., Niyo Y., Tiffany L. H.. Pathologic, hematologic, and serologic changes in rabbits given T-2 mycotoxin orally and exposed to aerosols of Aspergillus fumigatus conidia. American journal of veterinary research.  1988;49:2151–2160.

Thurman J. D., Creasia D. A., Trotter R. W.. Mycotoxicosis caused by aerosolized T-2 toxin administered to female mice. American journal of veterinary research.  1988;49:1928–1931.

Ryu J. C., Ohtsubo K., Izumiyama N., et al. The acute and chronic toxicities of nivalenol in mice. Fundamental and applied toxicology.  1988;11:38–47.

Pang V. F., Lambert R. J., Felsburg P. J., Beasley V. R., Buck W. B., Haschek W. M.. Experimental T-2 toxicosis in swine following inhalation exposure: clinical signs and effects on hematology, serum biochemistry, and immune response. Fundamental and applied toxicology.  1988;11:100–109.

Bauer J.. Disease and depression of productivity in raising swine caused by mycotoxins. Tierärztliche Praxis. Supplement.  1988;3:40–47.

Schiefer H. B., Rousseaux C. G., Hancock D. S., Blakley B. R.. Effects of low-level long-term oral exposure to T-2 toxin in CD-1 mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1987;25:593–601.

Hewetson J. F., Pace J. G., Beheler J. E.. Detection and quantitation of T-2 mycotoxin in rat organs by radioimmunoassay. Journal – Association of Official Analytical Chemists.  1987;70:654–657.

Pang V. F., Lambert R. J., Felsburg P. J., Beasley V. R., Buck W. B., Haschek W. M.. Experimental T-2 toxicosis in swine following inhalation exposure: effects on pulmonary and systemic immunity, and morphologic changes.  Toxicologic pathology.  1987;15:308–319.

Pang V. F., Swanson S. P., Beasley V. R., Buck W. B., Haschek W. M.. The toxicity of T-2 toxin in swine following topical application. I. Clinical signs, pathology, and residue concentrations. Fundamental and applied toxicology.  1987;9:41–49.

Pang V. F., Lorenzana R. M., Beasley V. R., Buck W. B., Haschek W. M.. Experimental T-2 toxicosis in swine. III. Morphologic changes following intravascular administration of T-2 toxin. Fundamental and applied toxicology.  1987;8:298–309.

Forsell J. H., Jensen R., Tai J. H., Witt M., Lin W. S., Pestka J. J.. Comparison of acute toxicities of deoxynivalenol (vomitoxin) and 15-acetyldeoxynivalenol in the B6C3F1 mouse. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1987;25:155–162.

Creasia D. A., Thurman J. D., Jones L. J., et al. Acute inhalation toxicity of T-2 mycotoxin in mice. Fundamental and applied toxicology.  1987;8:230–235.

Fairhurst S., Marrs T. C., Parker H. C., Scawin J. W., Swanston D. W.. Acute toxicity of T2 toxin in rats, mice, guinea pigs, and pigeons.  Toxicology.  1987;43:31–49.

Rensburg D. F., Thiel P. G., Jaskiewicz K.. Short-term effects of two fusarium toxins, diacetoxyscirpenol and neosolaniol monoacetate, in male Wistar rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1987;25:767–771.

Milczewski K.. Toxicity of epoxy trichothecenes in cultured mammalian cells. Mycotoxin research.  1987;3:69–76.

Pang V. F., Felsburg P. J., Beasley V. R., Buck W. B., Haschek W. M.. The toxicity of T-2 toxin in swine following topical application. II. Effects on hematology, serum biochemistry, and immune response. Fundamental and applied toxicology.  1987;9:50–59.

Schiefer H. B., Hancock D. S., Bhatti A. R.. Systemic effects of topically applied trichothecenes. I. Comparative study of various trichothecenes in mice. Zentralblatt für Veterinärmedizin. Reihe A.  1986;33:373–383.

Gabal M. A., Awad Y. L., Morcos M. B., Barakat A. M., Malik G.. Fusariotoxicoses of farm animals and mycotoxic leucoencephalomalacia of the equine associated with the finding of trichothecenes in feedstuffs.  Veterinary and human toxicology.  1986;28:207–212.

Arnold D. L., Karpinski K. F., McGuire P. F., et al. A short-term feeding study with deoxynivalenol (vomitoxin) using rats. Fundamental and applied toxicology.  1986;6:691–696.

Forsell J. H., Witt M. F., Tai J. H., Jensen R., Pestka J. J.. Effects of 8-week exposure of the B6C3F1 mouse to dietary deoxynivalenol (vomitoxin) and zearalenone. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1986;24:213–219.

Arnold D. L., McGuire P. F., Nera E. A., et al. The toxicity of orally administered deoxynivalenol (vomitoxin) in rats and mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1986;24:935–941.

Conner M. W., Camargo J., Punyarit P., Riengropitak S., Rogers A. E., Newberne P. M.. Toxicity of anguidine in mice. Fundamental and applied toxicology.  1986;7:153–164.

Coppock R. W., Gelberg H. B., Hoffmann W. E., Buck W. B.. The acute toxicopathy of intravenous diacetoxyscirpenol (anguidine) administration in swine.  Fundamental and applied toxicology.  1985;5:1034–1049.

Kravchenko L. V., Levitskaia A. B., Avren’eva L. I., Kranauskas A. E., Liukova G. V.. Biochemical, hematological and immunological criteria for assessing chronic T-2 mycotoxicosis in mice. Voprosy pitaniia.  1985:60–64.

Morrissey R. E., Norred W. P., Vesonder R. F.. Subchronic toxicity of vomitoxin in Sprague-Dawley rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  1985;23:995–999.

Bergmann F., Yagen B., Soffer D.. Toxic and lethal effects of T-2 toxin upon intracerebral administration to rats. Archives of toxicology.  1985;58:40–44.

Schiefer H. B., Nicholson S., Kasali O. B., Hancock D. S., Greenhalgh R.. Pathology of acute 3-acetyldeoxynivalenol toxicity in mice. Canadian journal of comparative medicine. Revue canadienne de médecine comparée.  1985;49:315–318.

Kasali O. B., Schiefer H. B., Hancock D. S., Blakley B. R., Tomar R. S., Greenhalgh R.. Subacute toxicity of dietary 3-acetyldeoxynivalenol in mice. Canadian journal of comparative medicine. Revue canadienne de médecine comparée.  1985;49:319–322.

Levitskaia A. B., Avren’eva L. I., Tutel’ian V. A.. Toxicological characteristics of acute and subacute T-2 mycotoxicosis in mice.  Voprosy pitaniia.  1985:59–62.

Trenholm H. L., Thompson B. K., Hartin K. E., Greenhalgh R., McAllister A. J.. Ingestion of vomitoxin (deoxynivalenol)-contaminated wheat by nonlactating dairy cows. Journal of dairy science.  1985;68:1000–1005.

Coppock R. W., Swanson S. P., Gelberg H. B., et al. Preliminary study of the pharmacokinetics and toxicopathy of deoxynivalenol (vomitoxin) in swine. American journal of veterinary research.  1985;46:169–174.

Schiefer H. B.. Systemic effects of topical application of trichothecenes in rodents. Archives belges = Belgisch archief.  1984;Suppl:223–225.

Côté L. M., Reynolds J. D., Vesonder R. F., et al. Survey of vomitoxin-contaminated feed grains in midwestern United States, and associated health problems in swine. Journal of the American Veterinary Medical Association.  1984;184:189–192.

Schiefer H. B., Hancock D. S.. Systemic effects of topical application of T-2 toxin in mice. Toxicology and applied pharmacology.  1984;76:464–472.

Kravchenko L. V., Khvylia S. I., Avren’eva L. I., Morozov I. A., Tutel’ian V. A.. Effect of T-2 toxin on organ ultrastructure and organelle-specific enzyme activity in rats. Tsitologiia.  1983;25:1264–1269.

Young L. G., McGirr L., Valli V. E., Lumsden J. H., Lun A.. Vomitoxin in corn fed to young pigs. Journal of animal science.  1983;57:655–664.

Friend S. C., Hancock D. S., Schiefer H. B., Babiuk L. A.. Experimental T-2 toxicosis in sheep. Canadian journal of comparative medicine. Revue canadienne de médecine comparée.  1983;47:291–297.

Kravchenko L. V., Avren’eva L. I., Tutel’ian V. A.. Effect of T-2 toxin on the activity of organelle-specific enzymes of various rat organs. Voprosy medit͡sinskoĭ khimii.  1983;29:113–117.

Long G. G., Diekman M., Tuite J. F., Shannon G. M., Vesonder R. F.. Effect of Fusarium roseum corn culture containing zearalenone on early pregnancy in swine. American journal of veterinary research.  1982;43:1599–1603.

Rafai P., Tuboly S.. Effect of T-2 toxin on adrenocortical function and immune response in growing pigs. Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B.  1982;29:558–565.

Hayes M. A., Schiefer H. B.. Comparative toxicity of dietary T-2 toxin in rats and mice. Journal of applied toxicology : JAT.  1982;2:207–212.

Jodczyk K. J., Rózański A., Bańkowski E.. [Superficial morphological and ultrastructural changes in BALB C/3T3 mouse cells cultured in a medium with an added verrucarin E analog WER I].  Patologia polska.  1982;33:61–69.

Stankushev Kh h., Duparinova M., Dzhurov A., Borisova L., Tacheva T.. [Clinical, morphological and biochemical changes in pigs caused by the toxic metabolites of Fusarium tricinctum]. Veterinarno-meditsinski nauki.  1981;18:31–38.

Duparinova M., Dzhurov A., Stankushev Kh h., Borisova L., Tacheva T.. [Clinical, morphological and biochemical changes in lambs caused by Fusarium toxins]. Veterinarno-meditsinski nauki.  1981;18:22–30.

Kriegleder H.. [Morphological findings in guinea pigs following acute and subacute diacetoxyscirpenol poisoning]. Zentralblatt für Veterinärmedizin. Reihe A.  1981;28:165–175.

Weaver G. A., Kurtz H. J., Bates F. Y., Mirocha C. J., Behrens J. C., Hagler W. M.. Diacetoxyscirpenol toxicity in pigs. Research in veterinary science.  1981;31:131–135.

Hayes M. A., Bellamy J. E., Schiefer H. B.. Subacute toxicity of dietary T-2 toxin in mice: morphological and hematological effects. Canadian journal of comparative medicine. Revue canadienne de médecine comparée.  1980;44:203–218.

Rukmini C., Prasad J. S., Rao K.. Effects of feeding T-2 toxin to rats and monkeys. Food and cosmetics toxicology.  1980;18:267–269.

Veselý D., Veselá D., Ritter J.. The occurrence of a toxigenic strain of Fusarium tricinctum in connection with disease in a dairy cow.  Veterinární medicína.  1979;24:397–402.

Weaver G. A., Kurtz H. J., Bates F. Y., et al. Acute and chronic toxicity of T-2 mycotoxin in swine. The Veterinary record.  1978;103:531–535.

DeNicola D. B., Rebar A. H., Carlton W. W., Yagen B.. T-2 toxin mycotoxicosis in the guinea-pig. Food and cosmetics toxicology.  1978;16:601–609.

Weaver G. A., Kurtz H. J., Mirocha C. J., Bates F. Y., Behrens J. C.. Acute toxicity of the mycotoxin diacetoxyscirpenol in swine. The Canadian veterinary journal. La revue vétérinaire canadienne.  1978;19:267–271.

Pier A. C., Cysewski S. J., Richard J. L., Baetz A. L., Mitchell L.. Experimental mycotoxicoses in calves with aflatoxin, ochratoxin, rubratoxin, and T-2 toxin. Proceedings, annual meeting of the United States Animal Health Association.  1976:130–148.

Sato N., Ueno Y., Enomoto M.. Toxicological approaches to the toxic metabolites of Fusaria. VIII. Acute and subacute toxicities of T-2 toxin in cats.  Japanese journal of pharmacology.  1975;25:263–270.

Hsu I. C., Smalley E. B., Strong F. M., Ribelin W. E.. Identification of T-2 toxin in moldy corn associated with a lethal toxicosis in dairy cattle.  Applied microbiology.  1972;24:684–690.

 

Birds

Lucke A, Doupovec B, Paulsen P, Zebeli Q, Böhm J. Effects of low to moderate levels of deoxynivalenol on feed and water intake, weight gain, and slaughtering traits of broiler chickens. Mycotoxin Res. 2017 Jul 7. PMID: 28687998

Broekaert N, Devreese M, De Boevre M, De Saeger S, Croubels S. T-2 Toxin-3α-glucoside in Broiler Chickens: Toxicokinetics, Absolute Oral Bioavailability, and in Vivo Hydrolysis. J Agric Food Chem. 2017 Jun 14;65(23):4797-4803. PMID: 28520442

Antonissen G, Devreese M, De Baere S, Martel A, Van Immerseel F, Croubels S. Impact of Fusarium mycotoxins on hepatic and intestinal mRNA expression of cytochrome P450 enzymes and drug transporters, and on the pharmacokinetics of oral enrofloxacin in broiler chickens. Food Chem Toxicol. 2017 Mar;101:75-83. PMID: 28082229

Antonissen G, De Baere S, Devreese M, Van Immerseel F, Martel A, Croubels S. Feed contamination with Fusarium mycotoxins induces a corticosterone stress response in broiler chickens. Poult Sci. 2017 Jan 1;96(1):14-17. PMID: 27591283

Yang X, Li L, Duan Y, Yang X. Antioxidant activity of JM113 in vitro and its protective effect on broiler chickens challenged with deoxynivalenol. J Anim Sci. 2017 Feb;95(2):837-846. PMID: 28380583

Grenier B, Dohnal I, Shanmugasundaram R, Eicher SD, Selvaraj RK, Schatzmayr G, Applegate TJ. Susceptibility of Broiler Chickens to Coccidiosis When Fed Subclinical Doses of Deoxynivalenol and Fumonisins-Special Emphasis on the Immunological Response and the Mycotoxin Interaction. Toxins (Basel). 2016 Jul 27;8(8). PMID: 27472362

Wan Q, He Q, Deng X, Hao F, Tang H, Wang Y. Systemic Metabolic Responses of Broiler Chickens and Piglets to Acute T-2 Toxin Intravenous Exposure. J Agric Food Chem. 2016 Jan 27;64(3):714-23. PMID: 26714875

Antonissen G, Haesendonck R, Devreese M, Broekaert N, Verbrugghe E, De Saeger S, Audenaert K, Haesebrouck F, Pasmans F, Ducatelle R, Croubels S, Martel A. The Impact of Deoxynivalenol on Pigeon Health: Occurrence in Feed, Toxicokinetics and Interaction with Salmonellosis. PLoS One. 2016 Dec 20;11(12):e0168205. PMID: 27997572

Jia R, Ma Q, Fan Y, Ji C, Zhang J, Liu T, Zhao L. The toxic effects of combined aflatoxins and zearalenone in naturally contaminated diets on laying performance, egg quality and mycotoxins residues in eggs of layers and the protective effect of Bacillus subtilis biodegradation product. Food Chem Toxicol. 2016 Apr;90:142-50. PMID: 26891816

Liu DW, Liu HY, Zhang HB, Cao MC, Sun Y, Wu WD, Lu CH. Potential natural exposure of endangered red-crowned crane (Grus japonensis) to mycotoxins aflatoxin B1, deoxynivalenol, zearalenone, T-2 toxin, and ochratoxin A. J Zhejiang Univ Sci B. 2016 Feb;17(2):158-68. PMID: 26834016

Schwartz-Zimmermann HE, Fruhmann P, Dänicke S, Wiesenberger G, Caha S, Weber J, Berthiller F. Metabolism of deoxynivalenol and deepoxy-deoxynivalenol in broiler chickens, pullets, roosters and turkeys. Toxins (Basel). 2015 Nov 12;7(11):4706-29. PMID: 26569307

Devreese M, Antonissen G, Broekaert N, De Baere S, Vanhaecke L, De Backer P, Croubels S. Comparative toxicokinetics, absolute oral bioavailability, and biotransformation of zearalenone in different poultry species. J Agric Food Chem. 2015 May 27;63(20):5092-8. PMID: 25947104

Pralatnet S, Poapolathep S, Imsilp K, Tanhan P, Isariyodom S, Kumagai S, Poapolathep A. The fate and tissue disposition of deoxynivalenol in broiler chickens. J Vet Med Sci. 2015 Sep;77(9):1151-5. PMID: 25843039

Sun YX, Yao X, Shi SN, Zhang GJ, Xu LX, Liu YJ, Fang BH. Toxicokinetics of T-2 toxin and its major metabolites in broiler chickens after intravenous and oral administration. J Vet Pharmacol Ther. 2015 Feb;38(1):80-5. PMID: 25079675

Xu L, Zhang G, Guo C, Zhang Y, Zhang Y, Zheng J, Yang H, Yang D, He L, Zeng Z, Fang B. Simultaneous determination of major type-B trichothecenes and the de-epoxy metabolite of deoxynivalenol in chicken tissues by HPLC-MS/MS. J Sep Sci. 2014 Mar;37(6):642-9. PMID: 24415673

Awad WA, Ghareeb K, Zentek J. Mechanisms underlying the inhibitory effect of the feed contaminant deoxynivalenolon glucose absorption in broiler chickens. Vet J. 2014 Oct;202(1):188-90. PMID: 25011710

Antonissen G, Van Immerseel F, Pasmans F, Ducatelle R, Haesebrouck F, Timbermont L, Verlinden M, Janssens GP, Eeckhaut V, Eeckhout M, De Saeger S, Hessenberger S, Martel A, Croubels S. The mycotoxin deoxynivalenol predisposes for the development of Clostridium perfringens-induced necrotic enteritis in broiler chickens. PLoS One. 2014 Sep 30;9(9):e108775. PMID: 25268498

Faixová Zita, Faix Stefan, Borutová Radka, Leng Lubomír. Effects of feeding diets contaminated with Fusarium mycotoxins on blood biochemical parameters of broiler chickens. Acta veterinaria Hungarica.  2010;58:275–285.

Sokolović Marijana, Garaj-Vrhovac Verica, Simpraga Borka. T-2 toxin: incidence and toxicity in poultry. Arhiv za higijenu rada i toksikologiju.  2008;59:43–52.

Borutova Radka, Faix Stefan, Placha Iveta, Gresakova Lubomira, Cobanova Klaudia, Leng Lubomir. Effects of deoxynivalenol and zearalenone on oxidative stress and blood phagocytic activity in broilers. Archives of animal nutrition.  2008;62:303–312.

Rezar V., Frankic T., Narat M., Levart A., Salobir J.. Dose-dependent effects of T-2 toxin on performance, lipid peroxidation, and genotoxicity in broiler chickens. Poultry science.  2007;86:1155–1160.

Chowdhury S. R., Smith T. K., Boermans H. J., Woodward B.. Effects of feed-borne Fusarium mycotoxins on hematology and immunology of laying hens. Poultry science.  2005;84:1841–1850.

Konjević Dean, Srebocan Emil, Gudan Andrea, Lojkić Ivana, Severin Kresimir, Sokolović Marijana. A pathological condition possibly caused by spontaneous trichotecene poisoning in Brahma poultry: first report.  Avian pathology : journal of the W.V.P.A.  2004;33:377–380.

Madheswaran R., Balachandran C., Murali Manohar B.. Influence of dietary culture material containing aflatoxin and T(2) toxin on certain serum biochemical constituents in Japanese quail. Mycopathologia.  2004;158:337–341.

Grizzle Judith M., Kersten David B., McCracken Malcolm D., Houston Allan E., Saxton Arnold M.. Determination of the acute 50% lethal dose T-2 toxin in adult bobwhite quail: additional studies on the effect of T-2 mycotoxin on blood chemistry and the morphology of internal organs. Avian diseases.  2004;48:392–399.

Sklan D., Shelly M., Makovsky B., Geyra A., Klipper E., Friedman A.. The effect of chronic feeding of diacetoxyscirpenol and T-2 toxin on performance, health, small intestinal physiology and antibody production in turkey poults. British poultry science.  2003;44:46–52.

Swamy H. V., Smith T. K., Cotter P. F., Boermans H. J., Sefton A. E.. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers. Poultry science.  2002;81:966–975.

Garaleviciene D., Pettersson H., Elwinger K.. Effects on health and blood plasma parameters of laying hens by pure nivalenol in the diet. Journal of animal physiology and animal nutrition.  2002;86:389–398.

Dänicke S., Ueberschär K. H., Halle I., Matthes S., Valenta H., Flachowsky G.. On the effects of Fusarium toxin contaminated maize in laying hen feeding. Mycotoxin research.  2001;17 Suppl 1:62–66.

Rafai P., Pettersson H., Bata A., et al. Effect of dietary T-2 fusariotoxin concentrations on the health and production of white Pekin duck broilers. Poultry science.  2000;79:1548–1556.

Kubena L. F., Edrington T. S., Harvey R. B., et al. Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and T-2 toxin or deoxynivalenol in broiler chicks. Poultry science.  1997;76:1239–1247.

Boston S., Wobeser G., Gillespie M.. Consumption of deoxynivalenol-contaminated wheat by mallard ducks under experimental conditions. Journal of wildlife diseases.  1996;32:17–22.

Hedman R., Pettersson H., Engström B., Elwinger K., Fossum O.. Effects of feeding nivalenol-contaminated diets to male broiler chickens. Poultry science.  1995;74:620–625.

Pettersson H., Hedman R., Engström B., Elwinger K., Fossum O.. Nivalenol in Swedish cereals–occurrence, production and toxicity towards chickens.  Food additives and contaminants.  1995;12:373–376.

Kubena L. F., Edrington T. S., Kamps-Holtzapple C., Harvey R. B., Elissalde M. H., Rottinghaus G. E.. Influence of fumonisin B1, present in Fusarium moniliforme culture material, and T-2 toxin on turkey poults. Poultry science.  1995;74:306–313.

Kubena L. F., Harvey R. B., Edrington T. S., Rottinghaus G. E.. Influence of ochratoxin A and diacetoxyscirpenol singly and in combination on broiler chickens. Poultry science.  1994;73:408–415.

Kubena L. F., Smith E. E., Gentles A., et al. Individual and combined toxicity of T-2 toxin and cyclopiazonic acid in broiler chicks. Poultry science.  1994;73:1390–1397.

Neiger R. D., Johnson T. J., Hurley D. J., Higgins K. F., Rottinghaus G. E., Stahr H.. The short-term effect of low concentrations of dietary aflatoxin and T-2 toxin on mallard ducklings. Avian diseases.  1994;38:738–743.

Ványi A., Glávits R., Bata A., Kovács F.. Pathomorphological changes caused by T-2 trichothecene fusariotoxin in geese. Acta veterinaria Hungarica.  1994;42:447–457.

Diaz G. J., Squires E. J., Julian R. J., Boermans H. J.. Individual and combined effects of T-2 toxin and DAS in laying hens. British poultry science.  1994;35:393–405.

Bergsjø B., Herstad O., Nafstad I.. Effects of feeding deoxynivalenol-contaminated oats on reproduction performance in White Leghorn hens. British poultry science.  1993;34:147–159.

Ruff M. D., Huff W. E., Wilkins G. C.. Characterization of the toxicity of the mycotoxins aflatoxin, ochratoxin, and T-2 toxin in game birds. III. Bobwhite and Japanese quail. Avian diseases.  1992;36:34–39.

Huff W. E., Ruff M. D., Chute M. B.. Characterization of the toxicity of the mycotoxins aflatoxin, ochratoxin, and T-2 toxin in game birds. II. Ringneck pheasant. Avian diseases.  1992;36:30–33.

Harvey R. B., Kubena L. F., Huff W. E., Elissalde M. H., Phillips T. D.. Hematologic and immunologic toxicity of deoxynivalenol (DON)-contaminated diets to growing chickens. Bulletin of environmental contamination and toxicology.  1991;46:410–416.

Ademoyero A. A., Hamilton P. B., Cullen J. M.. Scirpentriol toxicity in young broiler chickens. Poultry science.  1991;70:2090–2093.

Windingstad R. M., Cole R. J., Nelson P. E., Roffe T. J., George R. R., Dorner J. W.. Fusarium mycotoxins from peanuts suspected as a cause of sandhill crane mortality. Journal of wildlife diseases.  1989;25:38–46.

Kubena L. F., Huff W. E., Harvey R. B., Phillips T. D., Rottinghaus G. E.. Individual and combined toxicity of deoxynivalenol and T-2 toxin in broiler chicks. Poultry science.  1989;68:622–626.

Manley R. W., Hulet R. M., Meldrum J. B., Larsen C. T.. Turkey poult tolerance to diets containing deoxynivalenol (vomitoxin) and salinomycin. Poultry science.  1988;67:149–152.

Kubena L. F., Harvey R. B., Phillips T. D., Holman G. M., Creger C. R.. Effects of feeding mature White Leghorn hens diets that contain deoxynivalenol (vomitoxin). Poultry science.  1987;66:55–58.

Huff W. E., Kubena L. F., Harvey R. B., et al. Individual and combined effects of aflatoxin and deoxynivalenol (DON, vomitoxin) in broiler chickens.  Poultry science.  1986;65:1291–1298.

Hamilton R. M., Thompson B. K., Trenholm H. L., Fiser P. S., Greenhalgh R.. Effects of feeding white Leghorn hens diets that contain deoxynivalenol (vomitoxin)-contaminated wheat. Poultry science.  1985;64:1840–1852.

Hamilton R. M., Trenholm H. L., Thompson B. K., Greenhalgh R.. The tolerance of White Leghorn and broiler chicks, and turkey poults to diets that contained deoxynivalenol (vomitoxin)-contaminated wheat. Poultry science.  1985;64:273–286.

Hayes M. A., Wobeser G. A.. Subacute toxic effects of dietary T-2 toxin in young mallard ducks. Canadian journal of comparative medicine. Revue canadienne de médecine comparée.  1983;47:180–187.

Robb J., Kirkpatrick K. S., Norval M.. Association of toxin-producing fungi with disease in broilers. The Veterinary record.  1982;111:389–390.

Moran E. T., Hunter B., Ferket P., Young L. G., McGirr L. G.. High tolerance of broilers to vomitoxin from corn infected with Fusarium graminearum.  Poultry science.  1982;61:1828–1831.

Hoerr F. J., Carlton W. W., Yagen B., Joffe A. Z.. Mycotoxicosis caused by either T-2 toxin or diacetoxyscirpenol in the diet of broiler chickens.  Fundamental and applied toxicology.  1982;2:121–124.

Hoerr F. J., Carlton W. W., Tuite J., Vesonder R. F., Rohwedder W. K., Szigeti G.. Experimental trichothecene mycotoxicosis produced in broiler chickens by Fusarium sporotrichiella var. sporotrichioides. Avian pathology : journal of the W.V.P.A.  1982;11:385–405.

Hoerr F. J., Carlton W. W., Yagen B.. Mycotoxicosis caused by a single dose of T-2 toxin or diacetoxyscirpenol in broiler chickens. Veterinary pathology.  1981;18:652–664.

Huff W. E., Doerr J. A., Hamilton P. B., Vesonder R. F.. Acute toxicity of vomitoxin (Deoxynivalenol) in broiler chickens. Poultry science.  1981;60:1412–1414.

Hoerr F. J., Carlton W. W., Yagen B.. The toxicity of T-2 toxin and diacetoxyscirpenol in combination for broiler chickens. Food and cosmetics toxicology.  1981;19:185–188.

Chi M. S., Robison T. S., Mirocha C. J., Reddy K. R.. Acute toxicity of 12,13-epoxytrichothecenes in one-day-old broiler chicks. Applied and environmental microbiology.  1978;35:636–640.

Pearson A. W.. Biochemical changes produced by Fusarium T-2 toxin in the chicken. Research in veterinary science.  1978;24:92–97.

Richard J. L., Cysewski S. J., Pier A. C., Booth G. D.. Comparison of effects of dietary T-2 toxin on growth, immunogenic organs, antibody formation, and pathologic changes in turkeys and chickens. American journal of veterinary research.  1978;39:1674–1679.

Chi M. S., Mirocha C. J., Kurtz H. J., et al. Acute toxicity of T-2 toxin in broiler chicks and laying hens. Poultry science.  1977;56:103–116.

Chi M. S., Mirocha C. J., Kurtz H. J., Weaver G., Bates F., Shimoda W.. Subacute toxicity of T-2 toxin in broiler chicks. Poultry science.  1977;56:306–313.

Speers G. M., Mirocha C. J., Christensen C. M., Behrens J. C.. Effects on laying hens of feeding corn invaded by two species of Fusarium and pure T-2 mycotoxin. Poultry science.  1977;56:98–102.

 

Fish

Matejova I, Faldyna M, Modra H, Blahova J, Palikova M, Markova Z, Franc A, Vicenova M, Vojtek L, Bartonkova J, Sehonova P, Hostovsky M, Svobodova Z. Effect of T-2 toxin-contaminated diet on common carp (Cyprinus carpio L.). Fish Shellfish Immunol. 2017 Jan;60:458-465. PMID: 27840172

Pérez-Acosta JA, Burgos-Hernandez A, Velázquez-Contreras CA, Márquez-Ríos E, Torres-Arreola W, Arvizu-Flores AA, Ezquerra-Brauer JM. An in vitro study of alkaline phosphatase sensitivity to mixture of aflatoxin B1 and fumonisin B1 in the hepatopancreas of coastal lagoon wild and farmed shrimp Litopenaeus vannamei. Mycotoxin Res. 2016 Aug;32(3):117-25. PMID: 27040818

Pietsch C, Junge R. Physiological responses of carp (Cyprinus carpio L.) to dietary exposure to zearalenone (ZEN). Comp Biochem Physiol C Toxicol Pharmacol. 2016 Oct;188:52-9. PMID: 27349726

Greco M, Pardo A, Pose G. Mycotoxigenic fungi and natural co-occurrence of mycotoxins in rainbow trout (Oncorhynchus mykiss) feeds. Toxins (Basel). 2015 Nov 5;7(11):4595-609. PMID: 26556374

Pietsch C, Kersten S, Valenta H, Dänicke S, Schulz C, Burkhardt-Holm P, Junge R. Effects of Dietary Exposure to Zearalenone (ZEN) on Carp (Cyprinus carpio L.). Toxins (Basel). 2015 Aug 26;7(9):3465-80. PMID: 26343724

Nácher-Mestre J, Serrano R, Beltrán E, Pérez-Sánchez J, Silva J, Karalazos V, Hernández F, Berntssen MH. Occurrence and potential transfer of mycotoxins in gilthead sea bream and Atlantic salmon by use of novel alternative feed ingredients. Chemosphere. 2015 Jun;128:314-20. PMID: 25754010

Tolosa J, Font G, Mañes J, Ferrer E. Natural occurrence of emerging Fusarium mycotoxins in feed and fish from aquaculture. J Agric Food Chem. 2014 Dec 24;62(51):12462-70. PMID: 25432004

Matejova I, Modra H, Blahova J, Franc A, Fictum P, Sevcikova M, Svobodova Z. The effect of mycotoxin deoxynivalenol on haematological and biochemical indicators and histopathological changes in rainbow trout (Oncorhynchus mykiss). Biomed Res Int. 2014;2014:310680. PMID: 24729967

Pietsch C, Noser J, Wettstein FE, Burkhardt-Holm P. Unraveling the mechanisms involved in zearalenone-mediated toxicity in permanent fish cell cultures. Toxicon. 2014 Sep;88:44-61. PMID: 24950048

Sanden Monica, Jørgensen Susanne, Hemre Gro-Ingunn I., Ørnsrud Robin, Sissener Nini H.. Zebrafish (Danio rerio) as a model for investigating dietary toxic effects of deoxynivalenol contamination in aquaculture feeds. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.  2012;50:4441–4448.

Pietsch Constanze, Bucheli Thomas D., Wettstein Felix E., Burkhardt-Holm Patricia. Frequent biphasic cellular responses of permanent fish cell cultures to deoxynivalenol (DON). Toxicology and applied pharmacology.  2011;256:24–34.

Eppley R. M.. Sensitivity of brine shrimp (Artemia salina) to trichothecenes. Journal – Association of Official Analytical Chemists.  1974;57:618–620.

 

Insects

Purschke B, Scheibelberger R, Axmann S, Adler A, Jäger H. Impact of substrate contamination with mycotoxins, heavy metals and pesticides on growth performance and composition of black soldier fly larvae (Hermetia illucens) for use in the feed and food value chain. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Feb 26. PMID: 28278126

Zhang H, Zhang L, Diao X, Li N, Liu C. Toxicity of the mycotoxin fumonisin B1 on the insect Sf9 cell line. Toxicon. 2017 Apr;129:20-27. PMID: 28153490

Fornelli Francesca, Minervini Fiorenza, Mulè Giuseppina. Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line. In vitro cellular & developmental biology. Animal.  2004;40:166–171.

Duraĉková Z., Betina V., Horníková B., Nemec P.. Toxicity of mycotoxins and other fungal metabolites to Artemia salina larvae.  Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abt.: Allgemeine, landwirtschaftliche und technische Mikrobiologie.  1977;132:294–299.